{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:40:21Z","timestamp":1756284021364,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Collagenous sprue is a rare small bowel enteropathy that has overlapping clinical features with coeliac disease; it is commonly associated with arthritic autoimmune conditions, which often require non-steroidal anti-inflammatory drugs (NSAIDs). In the limited published literature available, there are putative suggestions of a link between NSAID use and collagen deposition in intestinal subepithelia in such patients. The authors present a case of a 43-year-old woman with long-standing NSAID use for autoimmune polyarthropathy and positive coeliac antibodies. However, distal duodenal biopsies revealed a thickened band of subepithelial collagen with villous atrophic appearances consistent with collagenous sprue. The patient was treated with a gluten-free diet and her NSAIDs were discontinued. After 6\u2005months, her gastrointestinal symptoms had resolved with complete histological resolution of the collagenous subepithelial bands and villous atrophy on duodenal biopsy.<\/jats:p>","DOI":"10.1136\/bcr-2013-200097","type":"journal-article","created":{"date-parts":[[2013,8,28]],"date-time":"2013-08-28T07:35:22Z","timestamp":1377675322000},"page":"bcr2013200097","source":"Crossref","is-referenced-by-count":5,"title":["Clinical and histological resolution of collagenous sprue following gluten-free diet and discontinuation of non-steroidal anti-inflammatory drugs (NSAIDs)"],"prefix":"10.1136","volume":"2013","author":[{"given":"D H","family":"Vasant","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Faculty of Medical and Human Sciences, Salford Royal Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Hayes","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Faculty of Medical and Human Sciences, Salford Royal Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Bucknall","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medical and Human Sciences, Salford Royal Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Faculty of Medical and Human Sciences, Salford Royal Foundation Trust, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, 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