{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:40:02Z","timestamp":1756366802455,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,3,10]]},"abstract":"<jats:p>A 71-year-old woman, with a history of light-chain amyloidosis, presented with a sudden onset dyspnoea. Echocardiography showed a large pericardial effusion with compression of the right atrium and the right ventricle. Right heart catheterisation demonstrated equalisation of her diastolic pressures consistent with cardiac tamponade. Pericardiocentesis revealed a haemmorrhagic exudative effusion with no evidence of malignancy. Bone marrow biopsy and other investigations showed no evidence of multiple myeloma. Her effusion recurred 2\u2005weeks later and repeat pericardiocentesis demonstrated similar findings. She was started on chemotherapy with no further recurrence of pericardial effusion. The patient was unable to tolerate chemotherapy and died 1\u2005year after initial presentation. This case represents a rare manifestation of cardiac amyloidosis and explores the reported aetiologies for cardiac tamponade in the setting of light-chain amyloidosis. Acute and definitive treatments are also discussed.<\/jats:p>","DOI":"10.1136\/bcr-2013-200248","type":"journal-article","created":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T07:38:24Z","timestamp":1396424304000},"page":"bcr2013200248","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Acute cardiac tamponade in light-chain amyloidosis"],"prefix":"10.1136","volume":"2014","author":[{"given":"Mikhail","family":"Kuprian","sequence":"first","affiliation":[{"name":"Madigan Army Medical Center, Tacoma, Washington, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Mount","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Madigan Army Medical Center, Tacoma, Washington, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,4,2]]},"reference":[{"key":"2025082800242663000_2014.apr02_1.bcr2013200248.1","first-page":"611","article-title":"Amyloidosis and cardiac involvement","volume":"151","author":"Cacoub","year":"2000","journal-title":"Ann Med Interne (Paris)"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.2","DOI":"10.1016\/S0735-1097(85)80475-7"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.3","DOI":"10.1136\/jcp.2004.017293"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.4","DOI":"10.1080\/10428190210182"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.5","DOI":"10.3109\/10428199609045727"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.6","DOI":"10.2169\/internalmedicine.48.1846"},{"key":"2025082800242663000_2014.apr02_1.bcr2013200248.7","first-page":"794","article-title":"Amyloidosis of the pericardium in multiple myeloma: an unusual cause of bloody pericardial effusion","volume":"29","author":"Kornberg","year":"1993","journal-title":"Isr J Med Sci"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.8","DOI":"10.1002\/ajh.21782"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.9","DOI":"10.1053\/j.ajkd.2006.03.036"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.10","DOI":"10.3343\/kjlm.2011.31.3.154"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.11","DOI":"10.1182\/blood.V97.6.1885"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.12","DOI":"10.1182\/blood-2011-07-370031"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.13","DOI":"10.1182\/blood-2011-01-330738"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.14","DOI":"10.1056\/NEJM199704243361702"},{"doi-asserted-by":"publisher","key":"2025082800242663000_2014.apr02_1.bcr2013200248.15","DOI":"10.1007\/s10157-009-0198-y"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200248","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:24:31Z","timestamp":1756365871000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,2]]},"references-count":15,"alternative-id":["10.1136\/bcr-2013-200248"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200248","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,4,2]]}}}