{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:58:27Z","timestamp":1756461507423,"version":"3.44.0"},"reference-count":26,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>We report a case of a young female patient with long-standing oral and genital Beh\u00e7et\u2019s disease (BD), who presented with progressive severe colonic inflammation and perforation, requiring multiple laparotomies. The case had ultimately a favourable outcome despite posing a number of diagnostic and therapeutic challenges. Intestinal complications, although rare, should be considered as important differential diagnoses in patients with BD presenting with abdominal pain, and is a difficult-to-prove differential diagnosis to Crohn's disease.<\/jats:p>","DOI":"10.1136\/bcr-2013-200253","type":"journal-article","created":{"date-parts":[[2013,8,5]],"date-time":"2013-08-05T09:58:05Z","timestamp":1375696685000},"page":"bcr2013200253","source":"Crossref","is-referenced-by-count":2,"title":["Intestinal complications of Beh\u00e7et\u2019s disease"],"prefix":"10.1136","volume":"2013","author":[{"given":"D Botond","family":"Kovacs","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, University Hospital North Tees, Stockton on Tees, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipak K","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Hospital North Tees, Stockton on Tees, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaushik","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospital North Tees, Stockton on Tees, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W","family":"Borowski","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, University Hospital North Tees, Stockton on Tees, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,8,5]]},"reference":[{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.1","first-page":"488","article-title":"Epidemiology of Adamantiades-Beh\u00e7et's disease","volume":"2013","author":"Zouboulis","year":"1999","journal-title":"Ann Med Interne"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.2","unstructured":"http:\/\/www.nhsinform.co.uk\/health-library\/articles\/b\/behcets-disease\/introduction (accessed 31 May 2013)."},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.3","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1136\/ard.55.3.208","article-title":"Gastrointestinal involvement in Beh\u00e7et's syndrome: a controlled study","volume":"2013","author":"Yurdakul","year":"1996","journal-title":"Ann Rheum Dis"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.4","unstructured":"Cheon JH Celik AF Kim WH . Beh\u00e7et's disease: gastrointestinal involvement. In: Yazici Y Yazici H , ed. Beh\u00e7et's syndrome. 1st edn. New York, NY: Springer, 2010:165\u201388."},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.5","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00004836-200003000-00006","article-title":"Gastrointestinal manifestations of Beh\u00e7et's disease","volume":"2013","author":"Bayraktar","year":"2000","journal-title":"J Clin Gastroenterol"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.6","first-page":"81","article-title":"Intestinal Beh\u00e7et's disease: surgical experience in seven cases","volume":"2013","author":"Sayek","year":"1991","journal-title":"Hepatogastroenterology"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.7","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1007\/s10350-006-0706-z","article-title":"Anti-Saccharomyces cerevisiae antibody in intestinal Beh\u00e7et's disease patients: relation to clinical course","volume":"2013","author":"Choi","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.8","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00054725-200108000-00010","article-title":"Colonoscopic findings in intestinal Beh\u00e7et's disease","volume":"2013","author":"Lee","year":"2001","journal-title":"Inflamm Bowel Dis"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.9","first-page":"925","article-title":"Proctitis in Beh\u00e7et disease. Study of 6 cases [in French]","volume":"2013","author":"Hamza","year":"1993","journal-title":"Rev Rhum Ed Fr"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.10","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00004836-200003000-00006","article-title":"Gastrointestinal manifestations of Beh\u00e7et's disease","volume":"2013","author":"Bayraktar","year":"2000","journal-title":"J Clin Gastroenterol"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.11","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00054725-200108000-00010","article-title":"Colonoscopic findings in intestinal Beh\u00e7et's disease","volume":"2013","author":"Lee","year":"2001","journal-title":"Inflamm Bowel Dis"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.12","first-page":"778","article-title":"A case of Beh\u00e7et's disease with multiple longitudinal ulcers all over the colon","volume":"2013","author":"Masugi","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.13","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1055\/s-2000-9012","article-title":"Prediction of the clinical course of Beh\u00e7et's colitis according to macroscopic classification by colonoscopy","volume":"2013","author":"Kim","year":"2000","journal-title":"Endoscopy"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.14","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s00261-002-0036-0","article-title":"Enteroclysis findings of intestinal Behcet disease: a comparative study with Crohn disease","volume":"2013","author":"Korman","year":"2003","journal-title":"Abdom Imaging"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.15","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1007\/s10620-009-1095-7","article-title":"Prediction of free bowel perforation in patients with intestinal Beh\u00e7et's disease using clinical and colonoscopic findings","volume":"2013","author":"Moon","year":"2010","journal-title":"Dig Dis Sci"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.16","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1002\/1529-0131(200111)44:11<2686::AID-ART448>3.0.CO;2-H","article-title":"A double-blind trial of colchicine in Behcet's syndrome","volume":"2013","author":"Yardacul","year":"2001","journal-title":"Arthritis Rheum"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.17","doi-asserted-by":"crossref","first-page":"443","DOI":"10.7326\/0003-4819-128-6-199803150-00004","article-title":"Thalidomide in the treatment of the mucocutaneous lesions of the Behcet's syndrome. A randomized, double blind, placebo controlled trial","volume":"2013","author":"Hamaryudan","year":"1998","journal-title":"Ann Intern Med"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.18","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1346-8138.2002.tb00263.x","article-title":"Dapsone in Behcet's disease: a double-blind, placebo-controlled, cross-over study","volume":"2013","author":"Sharquie","year":"2002","journal-title":"J Dermatol"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.19","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1056\/NEJM199002013220501","article-title":"A controlled trial of azathioprine in Behcet's syndrome","volume":"2013","author":"Yazici","year":"1990","journal-title":"N Engl J Med"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.20","first-page":"467","article-title":"Interferon alfa-2a in the treatment of Behcet's disease: a randomized placebo-controlled and double-blind study","volume":"2013","author":"Alpsoy","year":"2002","journal-title":"Arch Dermatol"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.21","first-page":"98","article-title":"Short-term trial of etanercept in Behcet's disease: a double blind, placebo controlled study","volume":"2013","author":"Melikoglu","year":"2005","journal-title":"J Rheumatol"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.22","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/rheumatology\/kem034","article-title":"Anti-TNF therapy in the management of Beh\u00e7et's disease\u2014review and basis for recommendations","volume":"2013","author":"Sfikakis","year":"2007","journal-title":"Rheumatology"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.23","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1007\/s10620-009-1095-7","article-title":"Prediction of free bowel perforation in patients with intestinal Beh\u00e7et's disease using clinical and colonoscopic findings","volume":"2013","author":"Moon","year":"2010","journal-title":"Dig Dis Sci"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.24","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10620-008-0337-4","article-title":"Gastrointestinal manifestations of Beh\u00e7et's disease","volume":"2013","author":"Ebert","year":"2009","journal-title":"Dig Dis Sci"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.25","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF02604297","article-title":"Intestinal involvement in Beh\u00e7et's disease: review of 136 surgical cases in the Japanese literature","volume":"2013","author":"Kasahara","year":"1981","journal-title":"Dis Colon Rectum"},{"key":"2025082802260093000_2013.aug05_1.bcr2013200253.26","first-page":"103","article-title":"Mimicry and deception in inflammatory bowel disease and intestinal beh\u00e7et disease","volume":"2013","author":"Grigg","year":"2012","journal-title":"Gastroenterol Hepatol (NY)"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:26:10Z","timestamp":1756373170000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,5]]},"references-count":26,"alternative-id":["10.1136\/bcr-2013-200253"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200253","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,8,5]]}}}