{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:47:30Z","timestamp":1758631650347,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 32-year-old woman presented with bilateral periorbital oedema of 2\u2005days duration which progressed to proptosis, chemosis with diminution of vision rapidly within a week. She was a known case of adenocarcinoma of the rectum who was treated with surgery and chemotherapy 6\u2005months earlier. Metastasis workup carried out then was negative. On examination, she had bilateral axial proptosis with sluggish pupillary reactions with restricted extra ocular movements. Fundus examination was normal. Systemically, the patient was of poor build and was undernourished. Haemogram showed raised total counts and erythrocyte sedimentation rate. CT orbit and brain showed metastasis to the frontal bones and orbit. On investigating further, the patient had liver and lung metastasis. The patient was started on chemotherapy, but she succumbed to the disease within a week. This case is reported to highlight how bilateral orbital cellulitis can be a presenting sign of systemic metastasis in treated malignancies.<\/jats:p>","DOI":"10.1136\/bcr-2013-200262","type":"journal-article","created":{"date-parts":[[2013,7,2]],"date-time":"2013-07-02T10:12:14Z","timestamp":1372759934000},"page":"bcr2013200262","source":"Crossref","is-referenced-by-count":2,"title":["Truth under a masquerade!"],"prefix":"10.1136","volume":"2013","author":[{"given":"Sarita R J","family":"Gonsalves","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geover Joslen","family":"Lobo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Kasturba Medical College, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman","family":"Mendonca","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Father Muller Medical College, Mangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,7,2]]},"reference":[{"key":"2025082703594920000_2013.jul02_1.bcr2013200262.1","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1001\/archopht.1988.01060140567024","article-title":"Orbital metastases from prostate carcinoma","volume":"2013","author":"Boldt","year":"1988","journal-title":"Arch Ophthalmol"},{"key":"2025082703594920000_2013.jul02_1.bcr2013200262.2","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0161-6420(82)34779-X","article-title":"A case of prostatic carcinoma with bilateral orbital metastases and the review of the literature","volume":"2013","author":"Carriere","year":"1982","journal-title":"Ophthalmology"},{"key":"2025082703594920000_2013.jul02_1.bcr2013200262.3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1080\/01676830902897470","article-title":"Orbital metastasis: clinical features, management and outcome","volume":"2013","author":"Valenzuela","year":"2009","journal-title":"Orbit"},{"unstructured":"Chekrine T Hassouni A Hatime M . Orbital metastasis from mucinous adenocarcinoma of the rectum. 2013;2013:95\u20138.","key":"2025082703594920000_2013.jul02_1.bcr2013200262.4"},{"key":"2025082703594920000_2013.jul02_1.bcr2013200262.5","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1001\/archopht.1974.01010010286003","article-title":"Carcinoma metastatic to the eye and orbit\u2014a clinic pathologic study of 227 cases","volume":"2013","author":"Ferry","year":"1974","journal-title":"Arch Ophthalmol"},{"unstructured":"Volpe NJ Albert DM . Metastatic and orital secondary tumours, Albert and Jacobie. Principles and practice of ophthalmology. Philadelphia: WB Saunders company, 1994, 206\u201328.","key":"2025082703594920000_2013.jul02_1.bcr2013200262.6"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200262","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:59:58Z","timestamp":1756292398000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,2]]},"references-count":6,"alternative-id":["10.1136\/bcr-2013-200262"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200262","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,7,2]]}}}