{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:04:23Z","timestamp":1756425863095,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>We present a unique case of disseminated tuberculosis presenting initially in the eye solely as a choroidal mass without any inflammation, mimicking choroidal metastasis. A 19-year-old girl presented with a large choroidal mass lesion in the right eye. Systemic examination revealed axillary lymphadenopathy. A fundus fluorescein angiography, positron emission tomography scan, abdominal ultrasonography and raised biochemical markers such as serum CA-125 pointed towards the diagnosis of choroidal metastases with primary in the ovaries. Fine needle aspiration cytology of the adnexal mass and ascitic fluid revealed granulomatous inflammation with a negative acid-fast bacilli stain. A multiplex PCR of ascitic fluid for the sequence MPB64 and IS6110 was positive for tuberculosis. The final diagnosis of disseminated tuberculosis was made and the patient subsequently showed a good response to antitubercular therapy.<\/jats:p>","DOI":"10.1136\/bcr-2013-200286","type":"journal-article","created":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T06:15:20Z","timestamp":1375337720000},"page":"bcr2013200286","source":"Crossref","is-referenced-by-count":0,"title":["Unusual choroidal mass"],"prefix":"10.1136","volume":"2013","author":[{"given":"Swapnil Madhukar","family":"Parchand","sequence":"first","affiliation":[{"name":"Advanced Eye Centre, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kusum","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aman","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Advanced Eye Centre, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,8,1]]},"reference":[{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.survophthal.2003.10.009","article-title":"Ocular tuberculosis masquerading as ocular tumors","volume":"2013","author":"Demirci","year":"2004","journal-title":"Surv Ophthalmol"},{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/MD.0b013e3182574a0b","article-title":"Choroidal metastasis as a presenting manifestation of lung cancer: a report of 3 cases and systematic review of the literature","volume":"2013","author":"Singh","year":"2012","journal-title":"Medicine (Baltimore)"},{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.3","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/09273940500269939","article-title":"Successful management of tubercular subretinal granulomas","volume":"2013","author":"Gupta","year":"2006","journal-title":"Ocul Immunol Inflamm"},{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.4","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.survophthal.2007.08.015","article-title":"Intraocular tuberculosis\u2013an update","volume":"2013","author":"Gupta","year":"2007","journal-title":"Surv Ophthalmol"},{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.5","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.ygyno.2006.04.010","article-title":"Peritoneal tuberculosis mimicking advanced ovarian cancer: a retrospective review of 22 cases","volume":"2013","author":"Koc","year":"2006","journal-title":"Gynecol Oncol"},{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.6","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1136\/bjo.2010.182659","article-title":"The use of positron emission tomography\/CT in the diagnosis of tuberculosis-associated uveitis","volume":"2013","author":"Doycheva","year":"2011","journal-title":"Br J Ophthalmol"},{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.7","first-page":"1129","article-title":"Peritoneal tuberculosis revealed by carcinomatosis on CT scan and uptake at FDG-PET","volume":"2013","author":"Jeffry","year":"2003","journal-title":"BJOG"},{"key":"2025082804315953000_2013.jul31_2.bcr2013200286.8","first-page":"40","article-title":"Evaluating PCR, culture & histopathology in the diagnosis of female genital tuberculosis","volume":"2013","author":"Thangappah","year":"2011","journal-title":"Indian J Med Res"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200286","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:32:10Z","timestamp":1756380730000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,1]]},"references-count":8,"alternative-id":["10.1136\/bcr-2013-200286"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200286","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,8,1]]}}}