{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:37:38Z","timestamp":1787017058313,"version":"build-2736575974"},"reference-count":26,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 51-year-old woman with dermatomyositis (DM) on chronic immunosuppressive therapy was hospitalised for evaluation of haematuria. Surprisingly, abdominal imaging demonstrated pneumoperitoneum and pneumatosis intestinalis (PI). Her abdominal examination and white cell count were normal, but she subsequently developed nausea and fever. Owing to concern for perforation, a hemicolectomy was performed. Pathology revealed PI without inflammatory, ischaemic or neoplastic features, and she recovered uneventfully. Her immunosuppressive therapy was discontinued. Six months later, a follow-up CT of the abdomen revealed recurrence of PI. As she was asymptomatic, she was managed conservatively with resolution of PI on subsequent imaging. PI is characterised by the presence of gas within the wall of the intestine. Its aetiology is often unclear but this case highlights the association between PI and both immunosuppressive therapy and DM. A review of PI in patients with DM suggests that clinically stable patients may be observed, while avoiding surgical intervention.<\/jats:p>","DOI":"10.1136\/bcr-2013-200308","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T10:19:12Z","timestamp":1377253152000},"page":"bcr2013200308","source":"Crossref","is-referenced-by-count":15,"title":["Recurrent pneumatosis intestinalis in a patient with dermatomyositis"],"prefix":"10.1136","volume":"2013","author":[{"given":"Yousef","family":"Zarbalian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik C","family":"von Rosenvinge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Twadell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamal","family":"Mikdashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,8,23]]},"reference":[{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.1","first-page":"1747","article-title":"Pneumatosis intestinalis: a review","volume":"2013","author":"Heng","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.2","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1177\/014107689909200713","article-title":"Pneumatosis cystoides intestinalis in a patient with dermatomyositis","volume":"2013","author":"Morris-Stiff","year":"1999","journal-title":"J R Soc Med"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.4240\/wjgs.v3.i6.86","article-title":"Pneumatosis intestinalis and pneumoperitoneum on computed tomography: beware of non-therapeutic laparotomy","volume":"2013","author":"Hsueh","year":"2011","journal-title":"World J Gastrointest Surg"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.4","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1749-6632.2009.04807.x","article-title":"Pneumatosis intestinalis presenting in autoimmune diseases","volume":"2013","author":"Dovrish","year":"2009","journal-title":"Ann N Y Acad Sci"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.5","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s003840050031","article-title":"Pneumatosis coli: a proposed pathogenesis based on study of 25 cases and review of the literature","volume":"2013","author":"Gagliardi","year":"1996","journal-title":"Int J Colorectal Dis"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.6","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1001\/archsurg.138.1.68","article-title":"The spectrum of pneumatosis intestinalis","volume":"2013","author":"St Peter","year":"2003","journal-title":"Arch Surg"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.7","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/BF02249034","article-title":"Pneumatosis cystoides intestinalis in systemic lupus erythematosus with intestinal vasculitis: treatment with high dose prednisone","volume":"2013","author":"Cabrera","year":"1994","journal-title":"Clin Rheumatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.8","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1002\/art.22782","article-title":"Late-onset gastrointestinal pain in juvenile dermatomyositis as a manifestation of ischemic ulceration from chronic endarteropathy","volume":"2013","author":"Mamyrova","year":"2007","journal-title":"Arthritis Rheum"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.9","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1365-2036.2009.04190.x","article-title":"Review article: the gastrointestinal complications of myositis","volume":"2013","author":"Ebert","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1542\/peds.61.1.127","article-title":"Pneumatosis intestinalis associated with fatal childhood dermatomyositis","volume":"2013","author":"Fischer","year":"1978","journal-title":"Pediatrics"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.11","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1136\/ard.61.4.305","article-title":"Polymyositis as a cause of total gut failure","volume":"2013","author":"Hughes","year":"2002","journal-title":"Ann Rheum Dis"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.12","first-page":"499","article-title":"First case of pneumatosis cystoides intestinalis in adult dermatomyositis","volume":"2013","author":"Pasquier","year":"1993","journal-title":"J Rheumatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.13","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1093\/rheumatology\/keh285","article-title":"Refractory adult dermatomyositis with pneumatosis cystoides intestinalis treated with infliximab","volume":"2013","author":"Selva-O'Callaghan","year":"2004","journal-title":"Rheumatology (Oxford)"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.14","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00384-004-0680-7","article-title":"A case of pneumatosis cystoides intestinalis with dermatomyositis in which EUS was useful for the diagnosis","volume":"2013","author":"Nosho","year":"2005","journal-title":"Int J Colorectal Dis"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.15","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s10067-005-0179-9","article-title":"Additive contribution of multiple factors in the development of pneumatosis intestinalis: a case report and review of the literature","volume":"2013","author":"Saito","year":"2007","journal-title":"Clin Rheumatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.16","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.annder.2008.03.028","article-title":"[Pneumatosis cystoides intestinalis complicating paraneoplastic dermatomyositis]","volume":"2013","author":"Sbidian","year":"2008","journal-title":"Ann Dermatol Venereol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1346-8138.2007.00414.x","article-title":"Case of pneumatosis cystoides intestinalis in adult dermatomyositis","volume":"2013","author":"Xiao","year":"2008","journal-title":"J Dermatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.18","doi-asserted-by":"crossref","first-page":"610","DOI":"10.3109\/s10165-011-0551-3","article-title":"Three cases of pneumatosis intestinalis presenting in autoimmune diseases","volume":"2013","author":"Sagara","year":"2012","journal-title":"Mod Rheumatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.19","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/PL00011184","article-title":"Pneumatosis cystoides intestinalis in a patient with polymyositis","volume":"2013","author":"Kuroda","year":"2001","journal-title":"Clin Rheumatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.20","doi-asserted-by":"crossref","first-page":"260","DOI":"10.3109\/s10165-004-0304-7","article-title":"A case of pneumatosis cystoides intestinalis in a patient with polymyositis and interstitial pneumonia","volume":"2013","author":"Wada","year":"2004","journal-title":"Mod Rheumatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.21","doi-asserted-by":"crossref","first-page":"249","DOI":"10.4166\/kjg.2011.57.4.249","article-title":"[A case of pneumatosis cystoids intestinalis with polymyositis]","volume":"2013","author":"Lee","year":"2011","journal-title":"Korean J Gastroenterol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.22","doi-asserted-by":"crossref","first-page":"234","DOI":"10.5217\/ir.2011.9.3.234","article-title":"Pneumatosis cystoides intestinalis and partial abdominal obstruction in a patient with polymyositis","volume":"2013","author":"Kim","year":"2011","journal-title":"Intest Res"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.23","first-page":"483","article-title":"Pneumatosis intestinalis in a patient with polymyositis","volume":"2013","author":"Elkayam","year":"2001","journal-title":"Clin Exp Rheumatol"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.24","first-page":"1021","article-title":"Interstitial pneumonia, intestinal pseudo-obstruction and pneumatosis cystoides intestinalis associated with polymyositis: report of a case","volume":"2013","author":"Hanawa","year":"1982","journal-title":"Stomach Intestine"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.25","doi-asserted-by":"crossref","first-page":"808","DOI":"10.2169\/naika.74.808","article-title":"[A case of polymyositis with ileus-like symptoms and pneumatosis cystoides intestinalis, improved by the treatment of high-flow oxygen therapy.]","volume":"2013","author":"Park","year":"1985","journal-title":"Nihon Naika Gakkai Zasshi"},{"key":"2025042709071915000_2013.aug23_1.bcr2013200308.26","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0016-5085(98)70155-6","article-title":"Measurement of gastrointestinal motility in the GI laboratory","volume":"2013","author":"Camilleri","year":"1998","journal-title":"Gastroenterology"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:07:33Z","timestamp":1745755653000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,23]]},"references-count":26,"alternative-id":["10.1136\/bcr-2013-200308"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200308","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,23]]}}}