{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:09Z","timestamp":1756374009206,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 77-year-old man presented himself with shortness of breath that was initially felt to be due to an acute coronary event, largely due to a very elevated troponin I result and his medical history. He subsequently showed evidence to suggest a significant pneumonia. The most likely candidate organism responsible, from the history and test results, appeared to be <jats:italic>Legionella<\/jats:italic>. We present the case for a spuriously and extremely elevated troponin I result, being at least in part due the production of heterophil antibodies by <jats:italic>Legionella<\/jats:italic>.<\/jats:p>","DOI":"10.1136\/bcr-2013-200489","type":"journal-article","created":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T06:13:28Z","timestamp":1381731208000},"page":"bcr2013200489","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["An unusually high troponin I result in association with <i>Legionella<\/i> infection"],"prefix":"10.1136","volume":"2013","author":[{"given":"Abhijit","family":"Gill","sequence":"first","affiliation":[{"name":"Department of Cardiology, Hillingdon Hospital, Uxbridge, Middlesex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon William","family":"Dubrey","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hillingdon Hospital, Uxbridge, Middlesex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,10,14]]},"reference":[{"key":"2025082802091009000_2013.oct14_1.bcr2013200489.1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0009-8981(99)00077-7","article-title":"Tissue specificity of cardiac troponin I, cardiac troponin T and creatine kinase-MB","volume":"2013","author":"Apple","year":"1999","journal-title":"Clin Chim Acta"},{"key":"2025082802091009000_2013.oct14_1.bcr2013200489.2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.pcad.2007.01.002","article-title":"Use and misuse of cardiac troponins in clinical practice","volume":"2013","author":"Gupta","year":"2007","journal-title":"Prog Cardiovasc Dis"},{"key":"2025082802091009000_2013.oct14_1.bcr2013200489.3","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.clinbiochem.2005.01.019","article-title":"Heterophile antibodies produce spuriously elevated concentrations of cardiac troponin I in patients with Legionella pneumophila","volume":"2013","author":"Garcia-Mancebo","year":"2005","journal-title":"Clin Biochem"},{"key":"2025082802091009000_2013.oct14_1.bcr2013200489.4","doi-asserted-by":"crossref","unstructured":"Ghali S Lewis K Kazan V . Fluctuation of spuriously elevated troponin I: a case report. Case Rep Crit Care 2012;2012:585879. doi:10.1155\/2012\/585879","DOI":"10.1155\/2012\/585879"},{"key":"2025082802091009000_2013.oct14_1.bcr2013200489.5","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1128\/CMR.00052-09","article-title":"Molecular pathogenesis of infections caused by Legionella pneumophila","volume":"2013","author":"Newton","year":"2010","journal-title":"Clin Microbiol Rev"},{"key":"2025082802091009000_2013.oct14_1.bcr2013200489.6","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/00005792-199009000-00004","article-title":"New and emerging aetiologies for community-acquired pneumonia with implications for therapy. A prospective multi-center study of 359 cases","volume":"2013","author":"Fang","year":"1990","journal-title":"Medicine (Baltimore)"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:09:18Z","timestamp":1756372158000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,14]]},"references-count":6,"alternative-id":["10.1136\/bcr-2013-200489"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200489","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,10,14]]}}}