{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:53:10Z","timestamp":1760298790593,"version":"3.40.4"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Few cases of Crohn's disease complicated with meningitis and epidural abscess have been described in literature. We present a case of a 42-year-old former smoker female patient diagnosed with Crohn's disease in September 1995 (with severe nutritional problems). On 20 February 2012, she was admitted due to a probable sepsis (without any previous treatment). After several days she developed a confusion syndrome (probable Wernicke's disease). On 5 March 2012, the patient presented with a febrile episode of 39\u00b0C. Two days later, the patient presented aphasia and paraparesis, and 3\u2005days later she presented a complex partial status epilepticus. A lumbar puncture was performed and showed 131 leucocytes (63% granulocytes) and proteins 296.3. The abdominopelvic CT scan revealed a presacral collection that seem to extend cranially towards the lumbosacral spine. The lumbar MRI confirmed the lumbar epidural abscess secondary to the fistulisation of the presacral abscess.<\/jats:p>","DOI":"10.1136\/bcr-2013-200503","type":"journal-article","created":{"date-parts":[[2013,9,6]],"date-time":"2013-09-06T10:24:45Z","timestamp":1378463085000},"page":"bcr2013200503","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Complex partial status epilepticus in a patient with Crohn's disease"],"prefix":"10.1136","volume":"2013","author":[{"given":"Montserrat G","family":"Delgado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Vega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Santamarta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Caminal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,9,6]]},"reference":[{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1586\/egh.09.45","article-title":"Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history","volume":"2013","author":"Lees","year":"2009","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.2","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s00115-012-3682-7","article-title":"Neurological complications of inflammatory bowel diseases","volume":"2013","author":"Cieplik","year":"2013","journal-title":"Nervenarzt"},{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1586\/eci.12.87","article-title":"Crohn's as an immune deficiency: from apparent paradox to evolving paradigm","volume":"2013","author":"Vinh","year":"2013","journal-title":"Expert Rev Immunol"},{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.4","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1212\/WNL.41.4.606","article-title":"Bacterial meningitis and dorsal spinal epidural abscess caused by Crohn's disease","volume":"2013","author":"Hefter","year":"1991","journal-title":"Neurology"},{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.5","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1093\/clinids\/20.5.1428","article-title":"Crohn's disease complicated by meningitis and spinal epidural abscess","volume":"2013","author":"Wallace","year":"1995","journal-title":"Clin Infect Dis"},{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.6","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1023\/B:DDAS.0000042247.83365.53","article-title":"Meningitis and epidural abscess associated with fistulizing Crohn's disease","volume":"2013","author":"Maggiore","year":"2004","journal-title":"Dig Dis Sci"},{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.7","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1111\/j.1572-0241.2007.01353_9.x","article-title":"Pneumoencephalomeningitis complicating Crohn's disease: a case report","volume":"2013","author":"Ramsay","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"2025042709140637000_2013.sep06_1.bcr2013200503.8","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1002\/ibd.20641","article-title":"Meningitis in a patient with previously undiagnosed Crohn's disease","volume":"2013","author":"Almeida","year":"2009","journal-title":"Inflamm Bowel Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T16:14:20Z","timestamp":1745770460000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,6]]},"references-count":8,"alternative-id":["10.1136\/bcr-2013-200503"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200503","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,9,6]]}}}