{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:52:35Z","timestamp":1756385555200,"version":"3.44.0"},"reference-count":32,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 52-year-old man underwent two-dimensional echocardiogram which showed moderate to severe aortic regurgitation (AR) and dilated ascending aorta. CT angiography (CTA) showed dilated ascending aorta (5\u2005cm) and transoesophageal echocardiogram revealed bicuspid aortic valve. He underwent cardiac catheterisation which revealed triple vessel aneurysmal disease of the left anterior descending, left circumflex and right coronary artery. The patient underwent aortic graft placement for ascending aortic aneurysm and aortic valve replacement with a Saint Jude valve for severe AR. There was no history or stigmata of Kawasaki disease and workup for coronary artery aneurysm including vasculitis and connective tissue disorders was negative. Histopathology did not reveal evidence of active aortitis or dissection. His aneurysms are being observed by a yearly coronary CTA. We present a rare case of multiple coronary artery aneurysms associated with bicuspid aortic valve and ascending aortic aneurysm.<\/jats:p>","DOI":"10.1136\/bcr-2013-200553","type":"journal-article","created":{"date-parts":[[2013,11,6]],"date-time":"2013-11-06T06:53:40Z","timestamp":1383720820000},"page":"bcr2013200553","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Non-atherosclerotic multiple coronary artery aneurysms"],"prefix":"10.1136","volume":"2013","author":[{"given":"Rishi","family":"Bajaj","sequence":"first","affiliation":[{"name":"Division of Cardiology, University of Massachusetts Medical School, Saint Vincent Hospital, Worcester, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh","family":"Mamidala","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Massachusetts Medical School, Saint Vincent Hospital, Worcester, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhjot","family":"Bajaj","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Massachusetts Medical School, Saint Vincent Hospital, Worcester, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepti","family":"Kumar","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Massachusetts Medical School, Saint Vincent Hospital, Worcester, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,11,6]]},"reference":[{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.1","first-page":"244","article-title":"Multiple giant coronary artery aneurysms","volume":"2013","author":"Marla","year":"2009","journal-title":"Tex Heart Inst J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0033-0620(97)80024-2","article-title":"Review coronary artery aneurysm: a review","volume":"2013","author":"Syed","year":"1997","journal-title":"Prog Cardiovasc Dis"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1161\/01.CIR.67.1.134","article-title":"Aneurysmal coronary artery disease","volume":"2013","author":"Swaye","year":"1983","journal-title":"Circulation"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.4","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1136\/hrt.78.2.136","article-title":"The natural history of aneurysmal coronary artery disease","volume":"2013","author":"Demopoulos","year":"1997","journal-title":"Heart"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.5","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1536\/ihj.29.491","article-title":"Coronary aneurysms in a case of Ehlers-Danlos syndrome","volume":"2013","author":"Di Mario","year":"1988","journal-title":"Jpn Heart J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.6","first-page":"110","article-title":"Giant saccular aneurysm of the left main coronary artery","volume":"2013","author":"Tuncer","year":"2013","journal-title":"J Geriatr Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.7","first-page":"461","article-title":"Coronary artery aneurysm","volume":"2013","author":"Kelley","year":"2002","journal-title":"J Invasive Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.8","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.hlc.2011.02.009","article-title":"Congenital giant aneurysm of the left coronary artery","volume":"2013","author":"Berdajs","year":"2011","journal-title":"Heart Lung Circ"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0735-1097(02)01909-5","article-title":"Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease","volume":"2013","author":"Lamblin","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.10","first-page":"449","article-title":"Covered-stent treatment of coronary aneurysm after drug-eluting stent placement. Case report and literature review","volume":"2013","author":"Bajaj","year":"2010","journal-title":"Tex Heart Inst J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.11","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1093\/eurheartj\/ehm229","article-title":"Coronary aneurysms after drug-eluting stents implantation","volume":"2013","author":"Ruiz-Nodar","year":"2007","journal-title":"Eur Heart J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.12","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1080\/14017430410016413","article-title":"Coronary aneurysm after implantation of a paclitaxel-eluting stent","volume":"2013","author":"Vik-Mo","year":"2004","journal-title":"Scand Cardiovasc J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.13","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1016\/j.ijcard.2007.07.039","article-title":"Spontaneous resolution of multiple coronary aneurysms complicating drug eluting stent implantation","volume":"2013","author":"Gurvitch","year":"2008","journal-title":"Int J Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.14","first-page":"431","article-title":"Large coronary artery aneurysms. A study of 20 clinical cases in the elderly","volume":"2013","author":"Fareh","year":"1997","journal-title":"Arch Mal Coeur Vaiss"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.15","first-page":"7416","article-title":"Review coronary aneurysms","volume":"2013","author":"Gziut","year":"2008","journal-title":"Pol Arch Med Wewn"},{"issue":"(3 Pt 1)","key":"2025082702594654000_2013.nov06_1.bcr2013200553.16","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/0002-8703(91)90210-9","article-title":"Delayed rupture of right coronary artery after directional atherectomy for bail-out","volume":"2013","author":"Van Suylen","year":"1991","journal-title":"Am Heart J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.17","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1136\/hrt.40.4.393","article-title":"Coronary artery ectasia\u2014a variant of occlusive coronary arteriosclerosis","volume":"2013","author":"Swanton","year":"1978","journal-title":"Br Heart J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.18","first-page":"127","article-title":"Vasospasm in a coronary artery aneurysm","volume":"2013","author":"Gutowski","year":"1991","journal-title":"Cathet Cardiovasc Diagn"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.19","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/clc.4960291005","article-title":"Coronary artery aneurysm: a review","volume":"2013","author":"Pahlavan","year":"2006","journal-title":"Clin Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.20","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0002-9149(01)01680-0","article-title":"An intravascular ultrasound classification of angiographic coronary artery aneurysms","volume":"2013","author":"Maehara","year":"2001","journal-title":"Am J Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ijcard.2006.07.038","article-title":"CT diagnosis of coronary artery aneurysms","volume":"2013","author":"Tan","year":"2007","journal-title":"Int J Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.22","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/j.amjcard.2004.03.011","article-title":"Risk factors and outcomes in patients with coronary artery aneurysms","volume":"2013","author":"Baman","year":"2004","journal-title":"Am J Cardiol"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.23","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/0002-9343(77)90423-5","article-title":"Coronary artery aneurysms. Study of their etiology, clinical course and effect on left ventricular function and prognosis","volume":"2013","author":"Befeler","year":"1977","journal-title":"Am J Med"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.24","doi-asserted-by":"crossref","first-page":"657","DOI":"10.2459\/JCM.0b013e328348e58c","article-title":"Combined surgical and angioplasty management of coronary artery aneurysms including the giant form","volume":"2013","author":"Kopjar","year":"2011","journal-title":"J Cardiovasc Med"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.25","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1177\/000331970005100708","article-title":"Nonatherosclerotic aneurysm of the left circumflex coronary artery presenting with accelerated angina Pectoris: response to medical management\u2014a case report","volume":"2013","author":"Khan","year":"2000","journal-title":"Angiology"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.26","first-page":"376","article-title":"Nonsurgical management of left main coronary artery aneurysms","volume":"2013","author":"Lima","year":"2006","journal-title":"Tex Heart Inst J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.27","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.jtcvs.2005.04.004","article-title":"Surgical treatment of giant coronary artery aneurysm.","volume":"2013","author":"Li","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.28","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1749-8090-4-18","article-title":"Giant right coronary artery aneurysm\u2014case report and literature review","volume":"2013","author":"Jha","year":"2009","journal-title":"J Cardiothorac Surg"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.29","doi-asserted-by":"crossref","unstructured":"Nomura F Ohno T . In situ coronary-coronary bypass grafting for a huge left coronary aneurysm. Ann Thorac Cardiovasc Surg. Published Online First: 30 Aug 2013. doi:10.5761\/atcs.cr.13-00101.","DOI":"10.5761\/atcs.cr.13-00101"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.30","first-page":"432","article-title":"Fedak: bicuspid aortic valve syndrome: heterogeneous but predictable?","volume":"2013","author":"Paul","year":"2008","journal-title":"Eur Heart J"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.31","first-page":"III35","article-title":"Bicuspid aortic valves are associated with aortic dilatation out of proportion to coexistent valvular lesions","volume":"2013","author":"Keane","year":"2000","journal-title":"Circulation"},{"key":"2025082702594654000_2013.nov06_1.bcr2013200553.32","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0022-5223(03)00398-2","article-title":"Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation","volume":"2013","author":"Fedak","year":"2003","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200553","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:59:56Z","timestamp":1756288796000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,6]]},"references-count":32,"alternative-id":["10.1136\/bcr-2013-200553"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200553","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,11,6]]}}}