{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:42:28Z","timestamp":1756381348843,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,2,24]]},"abstract":"<jats:p>A 28-year-old woman presented with colicky abdominal pain for 3\u2005months. Pain was associated with episodes of vomiting, abdominal distension and constipation. She also had loss of weight for this duration. General physical examination was unremarkable and the abdomen was soft, with no palpable organomegaly. A CT of the abdomen showed small bowel and ascending colon dilation with multiple air fluid levels. There was also a short segment of circumferential bowel wall thickening and luminal narrowing in the hepatic flexure with sudden transition of bowel diameter. She underwent a right hemicolectomy after necessary preoperative investigations. Histopathology revealed signet ring cell carcinoma (SRCC). This case highlights the importance of detecting such a lesion in a young, otherwise fit woman. The challenge lies in early diagnosis and awareness of general practitioners about this aggressive form of colonic tumours.<\/jats:p>","DOI":"10.1136\/bcr-2013-200587","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T08:04:15Z","timestamp":1395302655000},"page":"bcr2013200587","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Primary colonic signet ring cell carcinoma in a young patient"],"prefix":"10.1136","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2260-1459","authenticated-orcid":false,"given":"Raghunath","family":"Prabhu","sequence":"first","affiliation":[{"name":"Department of Surgery, Kasturba Medical College, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Kumar","sequence":"additional","affiliation":[{"name":"UHNS, Warwickshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil","family":"Krishna","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Kasturba Medical College, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajgopal","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Kasturba Medical College, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,3,20]]},"reference":[{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn532"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02305663"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.3","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21166"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.4","first-page":"211","article-title":"IIc type early carcinoma of the rectum originating \u2018de novo\u2019, report of a case","volume":"18","author":"Tsujinaka","year":"1983","journal-title":"Stomach Intest"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.5","first-page":"695450","article-title":"Signet cell carcinoma of colon in a nineteen-year-old patient: a case report","volume":"2013","author":"Pamuk\u00e7u","year":"2013","journal-title":"Case Rep Oncol Med"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.6","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1951.01250030082009"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.7","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.3748\/wjg.v12.i21.3446","article-title":"Primary signet-ring cell carcinoma of the colon at early stage: a case report and a review of the literature","volume":"12","author":"Fu","year":"2006","journal-title":"World J Gastroenterol"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.8","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.2118"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.9","doi-asserted-by":"publisher","DOI":"10.1007\/BF02048335"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.10","unstructured":"Willis RA . Pathology of tumours. St. Louis: C. V. Mosby Company, 1948:402."},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.11","doi-asserted-by":"crossref","unstructured":"Ewing J . Neoplastic diseases: a treatise on tumours. 2nd edn. Philadelphia: W. B. Saunders Company, 1922:640.","DOI":"10.1097\/00000441-192208000-00015"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.12","doi-asserted-by":"crossref","unstructured":"Watanabe H Jass JR Sobin LH . Histological typing of oesophageal and gastric tumours: WHO international histological classification of tumors. 2nd edn. (Berlin, Germany: Springer-Verlag:1990.","DOI":"10.1007\/978-3-642-83920-7"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.13","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0932-1"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.14","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450110090034"},{"key":"2025082803581012000_2014.mar20_1.bcr2013200587.15","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djh275"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:58:19Z","timestamp":1756378699000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,20]]},"references-count":15,"alternative-id":["10.1136\/bcr-2013-200587"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200587","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,3,20]]}}}