{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T23:44:31Z","timestamp":1775000671494,"version":"3.50.1"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 26-year-old farmer underwent deep anterior lamellar keratoplasty (DALK) for keratoconus. After 3\u2005months, he presented with interface keratitis. Medical treatment failed and he underwent a repeat DALK. Microbiological scrapings from the interface revealed an infection caused by non-tuberculous mycobacteria. Despite the use of intensive antibiotic therapy and a repeat lamellar keratoplasty, the infiltrates recurred. The patient underwent therapeutic penetrating keratoplasty. Microbiology of the corneal tissue revealed growth of <jats:italic>Mycobacterium chelonae<\/jats:italic>, and on histopathology, the acid-fast bacilli were noted to be located deep at the pre-Descemet level. There was complete resolution of the infection with no episodes of recurrence and final best-corrected visual acuity was 20\/40 at 1\u2005year of follow-up. Medical therapy is unlikely to succeed in post-DALK interface keratitis and penetrating rather than lamellar keratoplasty may be considered the surgery of choice.<\/jats:p>","DOI":"10.1136\/bcr-2013-200641","type":"journal-article","created":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T07:24:53Z","timestamp":1381994693000},"page":"bcr2013200641","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Recurrent non-tuberculous mycobacterial keratitis after deep anterior lamellar keratoplasty for keratoconus"],"prefix":"10.1136","volume":"2013","author":[{"given":"Somasheila I","family":"Murthy","sequence":"first","affiliation":[{"name":"Cornea and Anterior Segment Service, LV Prasad Eye Institute, Hyderabad, Andrapradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajat","family":"Jain","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Service, LV Prasad Eye Institute, Bhubaneshwar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rishi","family":"Swarup","sequence":"additional","affiliation":[{"name":"Swarup Eye Centre, Hyderabad, Andrapradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virender S","family":"Sangwan","sequence":"additional","affiliation":[{"name":"Clinical Trial Center, Dr. Paul Dubord Chair in Cornea, LV Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,10,17]]},"reference":[{"key":"2025082707110678000_2013.oct17_1.bcr2013200641.1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1034\/j.1600-0420.1999.770223.x","article-title":"Rhodotorula species infection in corneal interface following lamellar keratoplasty\u2014a case report","volume":"2013","author":"Panda","year":"1999","journal-title":"Acta Ophthalmol Scand"},{"key":"2025082707110678000_2013.oct17_1.bcr2013200641.2","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1097\/ICO.0b013e3180ca9a61","article-title":"Candida interface keratitis after deep anterior lamellar keratoplasty-clinical, microbiologic, histopathologic and confocal microscopic reports","volume":"2013","author":"Kanavi","year":"2007","journal-title":"Cornea"},{"key":"2025082707110678000_2013.oct17_1.bcr2013200641.3","first-page":"774","article-title":"Recurrent interface abscess secondary to Acanthamoeba keratitis treated by deep anterior lamellar keratoplasty","volume":"2013","author":"Bi","year":"2012","journal-title":"Int J Ophthalmol"},{"key":"2025082707110678000_2013.oct17_1.bcr2013200641.4","doi-asserted-by":"crossref","unstructured":"Wessel JM Bachmann BO Meiller R . Fungal interface keratitis by Candida orthopsilosis following deep anterior lamellar keratoplasty. BMJ Case Rep. 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