{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T21:05:17Z","timestamp":1783803917324,"version":"3.55.0"},"reference-count":23,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Multiple myeloma involving the thyroid cartilage is a very uncommon disease entity. Only 10 cases have been reported in the international literature to date and as such it constitutes a rare and challenging diagnosis to make. We report the case of a 63-year-old man with a background of malignant melanoma and multiple myeloma both of which were in remission at the time of presentation. The patient presented with hoarseness and a large neck mass that turned out to be an extramedullary deposit of his previously treated multiple myeloma indicating disease relapse. The differential diagnosis of a mass in the thyroid cartilage is discussed. Despite its rarity, this diagnosis should be considered even in patients with no history of multiple myeloma, as it can arise de-novo in the thyroid cartilage (extramedullary plasmacytoma). The importance of the multidisciplinary team (MDT) approach as well as recent advances in treatment are also discussed.<\/jats:p>","DOI":"10.1136\/bcr-2013-200689","type":"journal-article","created":{"date-parts":[[2013,8,30]],"date-time":"2013-08-30T11:14:04Z","timestamp":1377861244000},"page":"bcr2013200689","source":"Crossref","is-referenced-by-count":9,"title":["Extramedullary relapse of multiple myeloma in the thyroid cartilage"],"prefix":"10.1136","volume":"2013","author":[{"given":"Hannah 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