{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T03:32:28Z","timestamp":1752982348406,"version":"3.40.4"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 12-month-old boy, with no medical history, was admitted for dyspnoea with no cough or fever. Chest auscultation revealed an expiratory wheezing with decreased right-sided breath sounds. Chest imaging revealed subcarinal adenopathy and a nodule in the right principal bronchus (RB). Bronchoscopy showed a major obstruction of the RB by a granuloma, and a smaller granuloma in the left principal bronchus. The granulation tissue was removed by laser section. Histological examination revealed a necrotising granulomatous inflammation, culture showed a<jats:italic>Mycobacterium avium complex<\/jats:italic>(MAC). Tests to rule out tuberculosis and immunodeficiency were negative. The diagnosis of an MAC endobronchial granuloma was ascertained and a multidrug therapy associating clarithromycin, rifampin and ethambutol was started. The clinical outcome was good after 3\u2005months of treatment and the bronchoscopy normalised after 1\u2005year. Although rare, the frequency of MAC respiratory infections in immunocompetent children can increase. Reporting these cases should help to optimise diagnosis and treatment.<\/jats:p>","DOI":"10.1136\/bcr-2013-200776","type":"journal-article","created":{"date-parts":[[2013,11,19]],"date-time":"2013-11-19T09:53:59Z","timestamp":1384854839000},"page":"bcr2013200776","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Endobronchial avium mycobacteria infection in an immunocompetent child"],"prefix":"10.1136","volume":"2013","author":[{"given":"Caroline","family":"Perisson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Nathan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Briac","family":"Thierry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harriet","family":"Corvol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,11,19]]},"reference":[{"key":"2025042709394068000_2013.nov19_1.bcr2013200776.1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0165-5876(00)00381-5","article-title":"Isolated endobronchial atypical mycobacterium in a child: a case report and review of the literature","volume":"2013","author":"Litman","year":"2000","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"2025042709394068000_2013.nov19_1.bcr2013200776.2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1365-2672.2012.05298.x","article-title":"Mycobacterium avium complex\u2014the role of potable water in disease transmission","volume":"2013","author":"Whiley","year":"2012","journal-title":"J Appl Microbiol"},{"key":"2025042709394068000_2013.nov19_1.bcr2013200776.3","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1007\/s002470100003","article-title":"Isolated intrathoracic presentation of Mycobacterium avium complex in an immunocompetent child","volume":"2013","author":"Osorio","year":"2001","journal-title":"Pediatr Radiol"},{"key":"2025042709394068000_2013.nov19_1.bcr2013200776.4","doi-asserted-by":"crossref","first-page":"e434","DOI":"10.1542\/peds.112.5.e434","article-title":"Intrathoracic disease from nontuberculous mycobacteria in children: two cases and a review of the literature","volume":"2013","author":"Nolt","year":"2003","journal-title":"Pediatrics"},{"key":"2025042709394068000_2013.nov19_1.bcr2013200776.5","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1164\/rccm.200604-571ST","article-title":"An official ATS\/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases","volume":"2013","author":"Griffith","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"2025042709394068000_2013.nov19_1.bcr2013200776.6","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1002\/ppul.21194","article-title":"Endobronchial atypical mycobacteria in an immunocompetent child","volume":"2013","author":"del Rio Camacho","year":"2010","journal-title":"Pediatr Pulmonol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200776","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T16:39:51Z","timestamp":1745771991000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,19]]},"references-count":6,"alternative-id":["10.1136\/bcr-2013-200776"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200776","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,11,19]]}}}