{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:40:05Z","timestamp":1756276805855,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>\n                  <jats:italic>Burkholderia cepacia<\/jats:italic>, a Gram-negative bacterium commonly found in water and soil, is a rare cause of endophthalmitis. The authors report a case of a penicillin-allergic patient who presented 15\u2005days after an uneventful injection of ranibizumab for neovascular age-related macular degeneration with culture-positive <jats:italic>B cepacia<\/jats:italic> endophthalmitis. Initial antibiotic therapy using non-penicillin-based medications was not successful in eradicating the bacteria. Subsequent treatment with a third-generation cephalosporin resulted in complete resolution of the infection. <jats:italic>B cepacia<\/jats:italic> should be included among the bacterial species that may cause endophthalmitis after intravitreal injections.<\/jats:p>","DOI":"10.1136\/bcr-2013-202075","type":"journal-article","created":{"date-parts":[[2014,2,13]],"date-time":"2014-02-13T06:20:33Z","timestamp":1392272433000},"page":"bcr2013202075","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["<i>Burkholderia cepacia<\/i> endophthalmitis, in a penicillin allergic patient, following a ranibizumab injection"],"prefix":"10.1136","volume":"2014","author":[{"given":"Norman","family":"Saffra","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Maimonides Medical Center, Brooklyn, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Moriarty","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Maimonides Medical Center, Brooklyn, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,2,13]]},"reference":[{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.1","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0002-9394(14)70380-0","article-title":"Microbiologic factors and visual outcome in the endophthalmitis vitrectomy study","volume":"122","author":"Endophthalmitis Vitrectomy Study Group","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31820a6a03"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.3","first-page":"167","article-title":"Risk of administering cephalosporin antibiotics to patients with histories of penicillin allergy","volume":"74","author":"Anne","year":"1995","journal-title":"Ann Allergy Asthma Immunol"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198109103051106"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(82)90176-0"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.6","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2012-302435"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.7","first-page":"488","article-title":"Intravitreal bevacizumab: safety of multiple doses from a single vial for consecutive patients","volume":"18","author":"Ng","year":"2012","journal-title":"Hong Kong Med J"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.8","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2012.199"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.9","doi-asserted-by":"publisher","DOI":"10.3109\/08820538.2011.570847"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.10","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1995.01100120009001"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.11","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.9.5225-5230.2003"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90527-4"},{"key":"2025082623020716000_2014.feb13_1.bcr2013202075.13","first-page":"753","article-title":"Pseudomonas cepacia endophthalmitis.","volume":"17","author":"Del Piero","year":"1985","journal-title":"Ann Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:02:18Z","timestamp":1756274538000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,13]]},"references-count":13,"alternative-id":["10.1136\/bcr-2013-202075"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202075","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,2,13]]}}}