{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T02:27:27Z","timestamp":1782613647159,"version":"3.54.5"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>We report the case of a 59-year-old Afro-Caribbean woman who presented with symptoms of anorexia, lethargy, abdominal distension and vomiting on the background of newly diagnosed multiple myeloma, treated with one cycle of cyclophosphamide\u2013thalidomide\u2013dexamethasone chemotherapy 20\u2005days previously. A diagnosis of subacute bowel obstruction was made; however, the aetiology of the obstruction remained elusive. Common electrolyte abnormalities were excluded and a midline laparotomy revealed minimal intra-abdominal adhesions. Histological examination of a small bowel mesentery biopsy showed inflammatory cell infiltrate composed of lymphocytes, eosinophils and occasional plasma cells with a foreign body giant cell reaction suggestive of worm infection. A postoperative stool sample revealed heavy infestation with the rhabditiform larvae of<jats:italic>Strongyloides stercoralis<\/jats:italic>. The patient recovered following ivermectin treatment. In the absence of other causality, we attribute the subacute bowel obstruction to<jats:italic>S stercoralis<\/jats:italic>hyperinfection, triggered by immunosuppression secondary to chemotherapy and multiple myeloma.<\/jats:p>","DOI":"10.1136\/bcr-2013-202234","type":"journal-article","created":{"date-parts":[[2014,1,27]],"date-time":"2014-01-27T11:17:54Z","timestamp":1390821474000},"page":"bcr2013202234","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["<i>Strongyloides stercoralis<\/i>hyperinfection presenting as subacute small bowel obstruction following immunosuppressive chemotherapy for multiple myeloma"],"prefix":"10.1136","volume":"2014","author":[{"given":"Adrian Matthew","family":"Shields","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashida","family":"Goderya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Atta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,1,27]]},"reference":[{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.12968\/hosp.2002.63.2.2072","article-title":"Acute intestinal obstruction: diagnosis and management","volume":"63","author":"Burke","year":"2002","journal-title":"Hosp Med"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.2","first-page":"194","article-title":"Strongyloidiasis: a multifaceted disease","volume":"7","author":"Ganesh","year":"2011","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.3","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1K302"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.4","doi-asserted-by":"publisher","DOI":"10.1086\/382484"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.5","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-78"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.6","first-page":"91","article-title":"Fatal case of gram negative bacterial sepsis associated with disseminated Strongyloidiasis in an immunocompromised patient","volume":"58","author":"Fasih","year":"2008","journal-title":"J Pak Med Assoc"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.7","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S1413-8670(10)70106-9","article-title":"Fatal Strongyloides stercoralis hyper-infection in a patient with multiple myeloma","volume":"14","author":"Yassin","year":"2010","journal-title":"Braz J Infect Dis"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.8","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.12.5.680-682.2005"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.2001.00407.x"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.10","doi-asserted-by":"crossref","first-page":"610","DOI":"10.4269\/ajtmh.2001.65.610","article-title":"Influence of human T-cell lymphocytotropic virus type 1 infection on serologic and skin tests for Strongyloidiasis","volume":"65","author":"Porto","year":"2001","journal-title":"Am J Trop Med Hyg"},{"key":"2025042702240316000_2014.jan27_1.bcr2013202234.11","doi-asserted-by":"publisher","DOI":"10.1186\/1749-7922-5-23"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:24:12Z","timestamp":1745745852000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,27]]},"references-count":11,"alternative-id":["10.1136\/bcr-2013-202234"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202234","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,27]]}}}