{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:04:19Z","timestamp":1762542259290,"version":"3.40.4"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Urticaria is a common disorder characterised by well-demarcated and intensely pruritic erythematous skin swellings. Common triggers include infection, allergic reactions or medications. While often idiopathic, the presence of urticaria can be associated with underlying systemic disease. We report a case of a patient who presented with diffuse and refractory urticaria. A thorough workup was conducted to determine the aetiology including routine age-appropriate cancer screening. Mammography revealed four lesions in the patient's left breast with biopsy consistent with invasive ductal carcinoma. Disappearance of the urticarial lesions with mastectomy suggests an association between breast malignancy and urticaria. Thus, refractory urticaria with unknown cause should prompt a thorough history, physical examination and review of age-appropriate cancer screening.<\/jats:p>","DOI":"10.1136\/bcr-2013-202494","type":"journal-article","created":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T12:14:49Z","timestamp":1390997689000},"page":"bcr2013202494","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Breast malignancy masquerading under the cloak of acute urticaria"],"prefix":"10.1136","volume":"2014","author":[{"given":"Erin","family":"O'Donnell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Havyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,1,29]]},"reference":[{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.122759"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.2","doi-asserted-by":"publisher","DOI":"10.1186\/1710-1492-7-1"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.3","first-page":"1","article-title":"Chronic urticaria resolving after resection of mucinous breast cancer","volume":"1","author":"Daniel Benjamin","year":"2010","journal-title":"J Clin Exp Dermatol Res"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.4","first-page":"49","article-title":"Urticaria associated with a small cell carcinoma of the lung","volume":"69","author":"Greiner","year":"2002","journal-title":"Cutis"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.12.040"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.6","first-page":"192","article-title":"Chronic urticaria associated with thyroid carcinoma: report of 4 cases","volume":"17","author":"Manganoni","year":"2007","journal-title":"J Investig Allergol Clin Immunol"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90127-9"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.8","doi-asserted-by":"crossref","first-page":"23","DOI":"10.5070\/D37GJ4V6DD","article-title":"Urticaria and lip fasciculation may be prodromal signs of brain malignancy","volume":"12","author":"Shamsadini","year":"2006","journal-title":"Dermatol Online J"},{"key":"2025042702270354000_2014.jan29_1.bcr2013202494.9","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1365-2133.1990.tb01449.x","article-title":"Chronic urticaria and cancer: an epidemiological study of 1155 patients","volume":"123","author":"Lindelof","year":"1990","journal-title":"Br J Dermatol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202494","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:27:15Z","timestamp":1745746035000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,29]]},"references-count":9,"alternative-id":["10.1136\/bcr-2013-202494"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202494","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,1,29]]}}}