{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:14:02Z","timestamp":1792714442984,"version":"4.5.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,2,19]]},"abstract":"<jats:p>Malignant eccrine spiradenoma (MES) is an extremely rare but aggressive tumour, resulting in high mortality. We report the first case in the UK of metastatic MES on the scalp of a 37-year-old man who initially presented with a raised nodular mass which had grown rapidly over a few months. Excision biopsy of the lesion was performed and histology confirmed MES with evidence of cytological atypia and necrosis. A further wide local excision of the lesion with a 1\u2005cm surgical margin was performed and full clearance was achieved. At 10-month follow-up another similar lesion had developed close to the previously excised area. A CT scan demonstrated metastatic lesions in the lungs, liver and pelvis, and subsequently chemotherapy was initiated. Although MES is uncommon, it has a high propensity to metastasise, therefore prompt identification, treatment and close follow-up of these tumours is essential.<\/jats:p>","DOI":"10.1136\/bcr-2013-202524","type":"journal-article","created":{"date-parts":[[2014,5,19]],"date-time":"2014-05-19T12:55:33Z","timestamp":1400504133000},"page":"bcr2013202524","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["A malignant eccrine spiradenoma of the scalp"],"prefix":"10.1136","volume":"2014","author":[{"given":"Whitney","family":"Chow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mat","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,5,19]]},"reference":[{"key":"2025042705125289000_2014.may19_1.bcr2013202524.1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0030-6665(20)30868-9","article-title":"Adnexal carcinomas of the skin","volume":"26","author":"Marenda","year":"1993","journal-title":"Otolaryngol Clin North Am"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1177\/000313489906500311","article-title":"Malignant eccrine spiradenoma: a previously unreported presentation and review of the literature","volume":"65","author":"Beekley","year":"1999","journal-title":"Am Surg"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.3","first-page":"388","article-title":"Malignant transformation of eccrine spiradenoma","volume":"11","author":"Dabska","year":"1972","journal-title":"Pol Med J"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.4","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31818b4143"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.5","first-page":"455","article-title":"Spiradenocarcinoma of the scalp","volume":"69","author":"Russ","year":"2002","journal-title":"Cutis"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.1999.08138.x"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.7","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199712000-00003"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32265.x"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.00226.x"},{"key":"2025042705125289000_2014.may19_1.bcr2013202524.10","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890715)64:2<366::AID-CNCR2820640204>3.0.CO;2-R"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202524","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:13:01Z","timestamp":1745755981000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,19]]},"references-count":10,"alternative-id":["10.1136\/bcr-2013-202524"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202524","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,19]]}}}