{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:26:53Z","timestamp":1782602813819,"version":"3.54.5"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Relapsing polychondritis (RP) is a rare autoimmune disease that affects cartilage and multiple organ system. We describe a case of RP presenting with fever, conjunctivitis and inflammatory signs of the right knee. Infectious and neoplastic diseases were excluded by imaging and laboratory examinations. After 17\u2005days of admission the patient reported coughing\u00a0and odynophagia, and, a physical examination showed red ears. Otorhinolaryngological examination demonstrated arytenoid chondritis. RP was diagnosed based on four McAdam\u2019s criteria. The patient was medicated with oral prednisone, and a positive clinical response was noted. Severe disease may require high doses of corticosteroids or immunosuppressive agents and the biological treatment may be beneficial. Beginning manifestations, such as fever, are often unspecific, leading to RP misdiagnosis. In this case, close attention to the patient\u2019s clinical history and a detailed physical examination were fundamental in concluding the correct diagnosis, and consequently beginning the appropriate medication.<\/jats:p>","DOI":"10.1136\/bcr-2013-202670","type":"journal-article","created":{"date-parts":[[2014,2,7]],"date-time":"2014-02-07T11:07:22Z","timestamp":1391771242000},"page":"bcr2013202670","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Fever of unknown origin in a patient with red ears: relapsing polychondritis"],"prefix":"10.1136","volume":"2014","author":[{"given":"Juliana Nunes","family":"Avila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana Bonacho","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gra\u00e7a","family":"Tavares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,2,7]]},"reference":[{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.1","doi-asserted-by":"crossref","first-page":"680","DOI":"10.20452\/pamw.805","article-title":"Relapsing polychondritis: case report and literature review","volume":"119:","author":"Pol","year":"2009","journal-title":"Pol Arch Med Wewn"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.2","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.883091"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197811302992202"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.4","doi-asserted-by":"crossref","unstructured":"Sato T Yamano Y Tomaru U . Serum level of soluble triggering receptor expresses on myeloid cells-1 as a biomarker of disease activity in relapsing polychondritis. Mod Rheumatol 2013. http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23404524","DOI":"10.1007\/s10165-013-0833-z"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.5","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.2169\/internalmedicine.51.8561","article-title":"Recurrent anterior uveitis with hypopyon revealing relapsing polychondritis","volume":"51","author":"Salah","year":"2012","journal-title":"Intern Med"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-6519(03)78473-8"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.7","first-page":"84","article-title":"Tracheomalacia bronchomalacia: a severe complication of relapsing polychondritis","volume":"91","author":"Bem Salah","year":"2013","journal-title":"Tunis Med"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2013.03.002"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.9","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701457"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.10","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken468"},{"key":"2025042702351511000_2014.feb06_2.bcr2013202670.11","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.120381"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:35:26Z","timestamp":1745746526000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,7]]},"references-count":11,"alternative-id":["10.1136\/bcr-2013-202670"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202670","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,7]]}}}