{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T12:52:29Z","timestamp":1780491149092,"version":"3.54.1"},"reference-count":21,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,2,25]]},"abstract":"<jats:p>Russell body gastritis (RBG) is a rare entity with unestablished pathophysiology, endoscopic findings, clinical manifestations and treatments. Literature is scarce on this clinical entity with unclear clinical significance. Of 18 cases reported, 12 tested (+) for <jats:italic>Helicobacter pylori<\/jats:italic> and improved with treatment, but it remains unclear whether this link is coincidental or bears some clinical significance. We describe a case of elderly woman who had a follow-up oesophagogastroduodenoscopy for chronic peptic ulcers, and biopsy showed positive immunohistochemical stains for \u03ba and \u03bb, indicating a polytypic population of plasma cells. Immunostaining for <jats:italic>H pylori<\/jats:italic> was negative. Biopsies were also (\u2212) for gastric carcinoma, lymphoma\u00a0and plasmacytoma. Considering her RGB-suggestive histology and her symptoms of bone pains and anaemia, multiple myeloma screening was considered clinically relevant. The purpose of this review was to educate clinicians and gastroenterologists about this unique entity and explore its association with multiple myeloma or other plamacytic malignancies.<\/jats:p>","DOI":"10.1136\/bcr-2013-202672","type":"journal-article","created":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T05:47:03Z","timestamp":1395812823000},"page":"bcr2013202672","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["<i>Helicobacter pylori<\/i>-negative Russell body gastritis: does the diagnosis call for screening for plasmacytic malignancies, especially multiple myeloma?"],"prefix":"10.1136","volume":"2014","author":[{"given":"Jagpal Singh","family":"Klair","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Girotra","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farshad","family":"Aduli","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,3,26]]},"reference":[{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.1","first-page":"179","article-title":"Multiple myeloma with numerous intranuclear Russell bodies","volume":"84","author":"Mart\u00edn-Noya","year":"1999","journal-title":"Haematologica"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.1998.tb03901.x"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.3","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i9.1234"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2003.04355.x"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.5","first-page":"365","article-title":"Observations on the formation and nature of Russell bodies","volume":"35","author":"White","year":"1954","journal-title":"Br J Exp Pathol"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.6","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2005.032185"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.7","first-page":"261","article-title":"Russell body gastritis in an HIV positive patient: case report and review of literature","volume":"76","author":"Bhalla","year":"2012","journal-title":"Conn Med"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.8","first-page":"929","article-title":"Russell body gastritis","volume":"109","author":"Miura","year":"2012","journal-title":"Nihon Shokakibyo Gakkai Zasshi"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.9","first-page":"271","article-title":"Plasma cell alterations in ulcerative colitis. An electron microscopic study","volume":"11","author":"Gebbers","year":"1976","journal-title":"Pathol Eur"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.10","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.23.7.608"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.11","doi-asserted-by":"crossref","first-page":"915","DOI":"10.5858\/2004-128-915-RBGAUT","article-title":"Russell body gastritis: an unusual, tumor-like lesion of the gastric mucosa","volume":"128","author":"Erbersdobler","year":"2004","journal-title":"Arch Pathol Lab Med"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.12","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-005-1215-5"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.13","doi-asserted-by":"publisher","DOI":"10.1177\/106689690601400206"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2006.00443.x"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2007.01.009"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.16","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1027656"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.17","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21702"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2011.03876.x"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.19","doi-asserted-by":"publisher","DOI":"10.1177\/1066896911416115"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.20","first-page":"97","article-title":"Russell body gastritis: case report and review of the literature","volume":"21","author":"Karabagli","year":"2012","journal-title":"J Gastrointestin Liver Dis"},{"key":"2025082623574972000_2014.mar26_1.bcr2013202672.21","unstructured":"Yoon JB Lee TY Lee JS . Two cases of Russell body gastritis treated by Helicobacter pylori eradication."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202672","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:57:57Z","timestamp":1756277877000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,26]]},"references-count":21,"alternative-id":["10.1136\/bcr-2013-202672"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202672","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,26]]}}}