{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T12:53:13Z","timestamp":1766407993110,"version":"3.40.4"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>New onset refractory status epilepticus (NORSE) is a neurological emergency and difficult to treat condition. We report a case of involuntary movements resulting from thiopentone sodium infusion during the management of refractory status epilepticus. A young woman was admitted with fever and NORSE in the neurology intensive care unit. In addition to supportive measures, she was treated with intravenous lorazepam, phenytoin sodium, sodium valproate, midazolam and thiopentone sodium. While on thiopentone sodium, she developed involuntary twitches involving her upper limbs and face with EEG showing no evidence of ongoing status epilepticus. Because of the temporal relationship with thiopentone infusion, we tapered the dose of thiopentone sodium, which resulted in the disappearance of the movements. The patient recovered well with no recurrence of the seizures during the hospital stay.<\/jats:p>","DOI":"10.1136\/bcr-2013-202691","type":"journal-article","created":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T12:12:52Z","timestamp":1392120772000},"page":"bcr-2013-202691","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Refractory status epilepticus complicated by drug-induced involuntary movements"],"prefix":"10.1136","volume":"2014","author":[{"given":"Pradeep Pankajakshan","family":"Nair","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaibhav","family":"Wadwekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya","family":"Murgai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil K","family":"Narayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,2,11]]},"reference":[{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1684\/epd.2009.0266","article-title":"Complex partial status epilepticus revealing anti-NMDA receptor encephalitis","volume":"11","author":"Bayreuther","year":"2009","journal-title":"Epileptic Disord"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.2","first-page":"429","article-title":"[Autoimmune encephalitis with anti-glutamate receptor antibody presenting as epilepsia partialis continua and action myoclonus: a case report]","volume":"47","author":"Kato","year":"2007","journal-title":"Rinsh\u014d Shinkeigaku Clin Neurol"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.3","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-198810000-00008"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.4","doi-asserted-by":"publisher","DOI":"10.1177\/1756285611403826"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2011.10.002"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.6","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1212\/01.WNL.0000154469.27522.EC","article-title":"West Nile virus presenting as opsoclonus-myoclonus cerebellar ataxia","volume":"64","author":"Khosla","year":"2005","journal-title":"Neurology"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.7","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr215"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.8","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1213\/00000539-199311000-00023","article-title":"Excitatory effects and electroencephalographic correlation of etomidate, thiopental, methohexital, and propofol","volume":"77","author":"Reddy","year":"1993","journal-title":"Anesth Analg"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.9","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2007.3.3.154"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.10","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(92)90366-7"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.11","doi-asserted-by":"crossref","first-page":"417","DOI":"10.47102\/annals-acadmedsg.V34N7p417","article-title":"The NORSE (new-onset refractory status epilepticus) syndrome: defining a disease entity","volume":"34","author":"Wilder-Smith","year":"2005","journal-title":"Ann Acad Med Singapore"},{"key":"2025042702372750000_2014.feb11_2.bcr-2013-202691.12","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5721-2"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202691","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:37:34Z","timestamp":1745746654000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,11]]},"references-count":12,"alternative-id":["10.1136\/bcr-2013-202691"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202691","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,2,11]]}}}