{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:05:13Z","timestamp":1762506313155,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,3,25]]},"abstract":"<jats:p>Patients with asplenia are prone to overwhelming infections due to encapsulated organisms. We report a 62-year-old man presenting with fever and weakness. His medical history was significant for splenectomy and owning a dog as pet. The patient on examination had evidence of animal bite and scratch marks on his lower extremity and developed dry gangrene of multiple digits of his upper extremity soon after admission. The patient's initial blood cultures were positive for Gram-negative rods, but no organism was identified. <jats:italic>Capnocytophaga canimorsus<\/jats:italic> was the suspected organism and the patient's antibiotics were tailored accordingly, with good clinical recovery. The patient\u2019 blood cultures finally grew <jats:italic>C canimorsus<\/jats:italic> on day 20 for which the patient had already been treated with prior clinical judgement. Physicians should be aware of this organism in the setting of sepsis in patients with asplenia and use appropriate antibiotics until further results are obtained.<\/jats:p>","DOI":"10.1136\/bcr-2013-202768","type":"journal-article","created":{"date-parts":[[2014,4,23]],"date-time":"2014-04-23T17:49:40Z","timestamp":1398275380000},"page":"bcr2013202768","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Overwhelming <i>Capnocytophaga canimorsus<\/i> infection in a patient with asplenia"],"prefix":"10.1136","volume":"2014","author":[{"given":"Lokesh","family":"Shahani","sequence":"first","affiliation":[{"name":"Department of Infectious Disease, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Khardori","sequence":"additional","affiliation":[{"name":"Eastern Virginia Medical School, Norfolk, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,4,23]]},"reference":[{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93331-3"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.2","first-page":"134","article-title":"Biochemical aspects of tuftsin deficiency syndrome","volume":"59","author":"Najjar","year":"1981","journal-title":"Med Biol"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.3","first-page":"1969","article-title":"Disorders of spleen","volume-title":"Wintrobe's clinical hematology","volume":"2","author":"Chapman","year":"1999"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.4","unstructured":"Shurin SB. The spleen and its disorders. In: Hoffman R, Benz EJ Jr, Shattil SJ, eds. Hoffman Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Churchill Livingstone Elsevier; 2008:821\u20139."},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.5","doi-asserted-by":"crossref","unstructured":"Ahmed M Khardori N . Severe infections in asplenic patients in critical care. Infect Dis Crit Care Med 2009:350\u20138.","DOI":"10.3109\/9781420092417.020"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.6","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(90)90259-G"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.7","unstructured":"Lutwick LI. Infections in asplenic patients. 6th ed. Mandell GL, Bennett JE, Dolin R, eds. Principle and practice of infectious diseases. Pennsylvania: Elsevier Churchill Livingstone; 2005, 3524\u201332."},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.8","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-73-3-433"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.9","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/ajcp\/65.4.564","article-title":"A previously undescribed Gram-negative bacillus causing septicemia and meningitis","volume":"65","author":"Bobo","year":"1976","journal-title":"Am J Clin Pathol"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.10","doi-asserted-by":"publisher","DOI":"10.1080\/000155501750208362"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.11","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.05274-0"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2007.12.031"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.13","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.133.12.1362"},{"key":"2025082706494219000_2014.apr23_1.bcr2013202768.14","doi-asserted-by":"crossref","first-page":"859","DOI":"10.5858\/2000-124-0859-WFSSTC","article-title":"Waterhouse-Friderichsen syndrome secondary to Capnocytophaga canimorsus septicemia and demonstration of bacteremia by peripheral blood smear","volume":"124","author":"Mirza","year":"2000","journal-title":"Arch Pathol Lab Med."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T13:49:47Z","timestamp":1756302587000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,23]]},"references-count":14,"alternative-id":["10.1136\/bcr-2013-202768"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202768","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,4,23]]}}}