{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T04:02:07Z","timestamp":1745812927786,"version":"3.40.4"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,6,6]]},"abstract":"<jats:p>We describe a rare occurrence of parathyroid hormone-related peptide (PTHrp) associated hypercalcaemia with a recurrence of transitional cell carcinoma of the renal pelvis. Our patient presented with serum calcium of 3.9\u2005mmol\/L, PTH of 5\u2005ng\/L and a PTHrp of 9.8\u2005pmol\/L (&lt;2\u2005pmol\/L). He had no evidence of metastatic disease. His hypercalcaemia responded to bisphosphonate therapy. He chose to be treated conservatively and died 5\u2005weeks after presentation. This is the seventh such case described in the literature. PTHrp-induced hypercalcaemia is associated with a grave prognosis, with a mean survival of 65\u2005days from presentation.<\/jats:p>","DOI":"10.1136\/bcr-2013-202796","type":"journal-article","created":{"date-parts":[[2014,6,20]],"date-time":"2014-06-20T10:21:32Z","timestamp":1403259692000},"page":"bcr2013202796","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["A rare complication of transitional cell carcinoma of the renal pelvis: parathyroid hormone-related peptide-induced hypercalcaemia"],"prefix":"10.1136","volume":"2014","author":[{"given":"Eoin","family":"O Sullivan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Plant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,6,20]]},"reference":[{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20006"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.2","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.urology.2003.12.005","article-title":"Transitional cell carcinoma of the renal pelvis associated with hypercalcemia in a patient with autosomal dominant polycystic kidney disease","volume":"63","author":"Grubb","year":"2004","journal-title":"Urology"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.3","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2004.187"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.4","doi-asserted-by":"publisher","DOI":"10.4158\/EP.10.2.125"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65104-X"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.6","first-page":"873","article-title":"A case of bladder tumor producing granulocyte-colony stimulation factor and parathyroid hormone-related protein","volume":"47","author":"Tsuchiya","year":"2001","journal-title":"Hinyokika Kiyo"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.7","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.33.107"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.8","first-page":"137","article-title":"Bladder carcinoma presenting with hypercalcemia: a case report","volume":"43","author":"Maeda","year":"1997","journal-title":"Hinyokika Kiyo"},{"key":"2025042705515835000_2014.jun20_1.bcr2013202796.9","first-page":"2136","article-title":"Transitional cell carcinoma of the bladder producing parathyroid hormone-related protein (PTHrP)","volume":"11","author":"Chaudhary","year":"2004","journal-title":"Can J Urol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-202796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:52:08Z","timestamp":1745758328000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-202796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,20]]},"references-count":9,"alternative-id":["10.1136\/bcr-2013-202796"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-202796","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,6,20]]}}}