{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T15:03:13Z","timestamp":1781276593054,"version":"3.54.1"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,2,10]]},"abstract":"<jats:p>We describe a case of a patient who presented with a 20-day history of vomiting, generalised weakness and loss of appetite and a 2-day history of altered sensorium. On examination, he was grossly emaciated and there were no palpable lymph nodes. Central nervous system examination revealed nystagmus with bilateral lateral recti palsy and abdominal examination showed mild hepatomegaly. MRI of the brain showed bilateral and symmetrical hypertense signal changes in T2-weighted and fluid-attenuated inversion recovery sequences with diffusion restriction in the paramedian ventromedial thalamus. These findings were compatible with Wernicke's encephalopathy. He was started on thiamine supplementation with which neurological signs improved. An ultrasound of the abdomen showed mild hepatomegaly with multiple hyperechoic lesions and wall thickening of the pyloric antrum. Upper gastroduodenoscopy showed ulcerative lesions involving the antrum, pylorus and duodenum. Biopsy revealed moderately differentiated adenocarcinoma. The patient underwent palliative gastrojejunostomy and was clinically better at discharge. It is important to consider Wernicke encephalopathy in patients with gastric cancer who have acute neurological symptoms.<\/jats:p>","DOI":"10.1136\/bcr-2013-203511","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T08:04:15Z","timestamp":1395302655000},"page":"bcr2013203511","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Wernicke's encephalopathy in a patient with gastric carcinoma: a diagnosis not to miss"],"prefix":"10.1136","volume":"2014","author":[{"given":"Chandrashekar","family":"Udyavara Kudru","sequence":"first","affiliation":[{"name":"Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivashankara","family":"Kaniyoor Nagiri","sequence":"additional","affiliation":[{"name":"Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,3,20]]},"reference":[{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-200202000-00010"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70104-7"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.3","unstructured":"Victor M Adams RD Collins GH . The Wernicke-Korsakoff syndrome and related neurologic disorders due to alcoholism and malnutrition. 2nd edn. Philadelphia, PA: FA Davis, 1989."},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.4","unstructured":"Victor M . The Wernicke-Korsakoff syndrome. In: Vinken PJ Bruyn GW . eds. Handbook of clinical neurology. vol 28, part II. Amsterdam: North-Holland; 1976:243\u201370."},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.5","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.49.4.341"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.6","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2010.42.2.77"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.7","doi-asserted-by":"publisher","DOI":"10.1159\/000052086"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196209202671204"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.9","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1007\/s00330-002-1624-7","article-title":"Wernicke encephalopathy: MR findings and clinical presentation","volume":"13","author":"Weidauer","year":"2003","journal-title":"Eur Radiol"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2005.07.002"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.11","first-page":"12","article-title":"Differential diagnosis of white matter diseases in the tropics: an overview","volume":"12","author":"Pandit","year":"2009","journal-title":"Ann Indian Acad Neurol"},{"key":"2025082707174701000_2014.mar20_1.bcr2013203511.12","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.alcalc.a008400"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-203511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:17:55Z","timestamp":1756304275000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-203511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,20]]},"references-count":12,"alternative-id":["10.1136\/bcr-2013-203511"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-203511","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,20]]}}}