{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:40:09Z","timestamp":1745757609637,"version":"3.40.4"},"reference-count":25,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,4,16]]},"abstract":"<jats:p>We present the first reported case of a concomitant Leydig cell tumour (LCT) and paratesticular leiomyoma in an adult man with a history of bilateral cryptorchidism. An 80-year-old man presented with a 2-month history of a left testicular lump associated with mild discomfort and a gradual increase in size on a background of bilateral cryptorchidism requiring multiple orchidopexy procedures as a child. Ultrasound confirmed a lesion suspicious for malignancy and he proceeded to a left radical orchidectomy. Histopathological assessment of the left testis revealed a concomitant testicular LCT with rare malignant features and paratesticular leiomyoma.<\/jats:p>","DOI":"10.1136\/bcr-2014-203682","type":"journal-article","created":{"date-parts":[[2014,5,21]],"date-time":"2014-05-21T10:56:53Z","timestamp":1400669813000},"page":"bcr2014203682","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["One lump or two? Concomitant Leydig cell tumour and paratesticular leiomyoma in an adult man"],"prefix":"10.1136","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4515-4145","authenticated-orcid":false,"given":"Diwei","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Jia Hui","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa","family":"Power","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajinder","family":"Singh-Rai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,5,21]]},"reference":[{"key":"2025042705172933000_2014.may21_2.bcr2014203682.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198503000-00002"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.2","unstructured":"Ulbright T Amin M Young R . Tumours of the testis, adnexa, spermatic cord, and scrotum. Atlas of tumor pathology. Washington, DC: Armed Forces Institute of Pathology, 1999."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.3","unstructured":"Eble J Sauter G Epstein J . Pathology and genetics of tumours of the urinary system and male genital organs. Lyon: IARC Press, 2004."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.4","unstructured":"Lawrence WD Young RH Scully RE . Sex cord-stromal tumours. Pathology of the testis and its adenxa. New York: Churchill Livingstone, 1986."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70201-9"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.6","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S0022-5347(17)58867-9","article-title":"Clinical management of non-testicular intrascrotal tumours","volume":"116","author":"Beccia","year":"1976","journal-title":"J Urol"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.7","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(82)90364-8"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.8","first-page":"2411","volume-title":"Neoplasm of testis. Campbell's urology","volume":"III","author":"Richie","year":"1998"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.9","first-page":"307","article-title":"Paratesticular soft tissue neoplasms","volume":"17","author":"Folpe","year":"2000","journal-title":"Semin Diagn Pathol"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10177.x"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.12.035"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.12","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/31653779"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.13","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.07.005"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.14","first-page":"60","article-title":"Unilateral malignant Leydig cell tumor of testis in a patient with contralateral cryptorchidism","volume":"6","author":"Efthimiou","year":"2009","journal-title":"J Urol"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.15","doi-asserted-by":"publisher","DOI":"10.3109\/00365599409180528"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.16","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1046\/j.1464-410x.1999.00959.x","article-title":"Unilateral Leydig cell tumour associated with a contralateral undescended testis","volume":"83","author":"Calleja","year":"1999","journal-title":"BJU Int"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70201-9"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.18","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1002\/1097-0142(19911115)68:10<2324::AID-CNCR2820681036>3.0.CO;2-K","article-title":"Treatment of malignant Leydig cell tumor","volume":"68","author":"Bertram","year":"1999","journal-title":"Cancer"},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.19","unstructured":"Albers P Albrecht W Algaba F . Guidelines on testicular cancer. Eur Assoc Urol 2008:23\u20135."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.20","unstructured":"Ro JY Kim KR Shen SS . Tumors and tumor-like conditions of the male genital tract. Diagnostic histopathology of tumors. 4th edn. Philadelphia: Elsevier Inc, 2013:977."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.21","unstructured":"Rosai J . Male reproductive system. Rosai and Ackerman's surgical pathology. 10th edn. Philadelphia: Elsevier Inc, 2011:1355\u20137."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.22","unstructured":"Ro JY Kim KR Shen SS . Tumors and tumor-like conditions of the male genital tract. In: Fletcher CD , ed. Diagnostic histopathology of tumors. 4th edn. Philadelphia: Elsevier Inc, 2013:990\u20135."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.23","unstructured":"Miettinen MM Quade B . Leiomyoma of deep soft tissue. WHO classification of tumours of soft tissue and bone. 4th edn. Lyon: International Agency for Research on Cancer, 2013:110\u201311."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.24","unstructured":"Lazar A Evans HL Shipley J . Leiomyosarcoma. WHO classification of tumours of soft tissue and bone. 4th edn. Lyon: International Agency for Research on Cancer, 2013:111\u201313."},{"key":"2025042705172933000_2014.may21_2.bcr2014203682.25","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912023412304"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-203682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:17:40Z","timestamp":1745756260000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-203682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,21]]},"references-count":25,"alternative-id":["10.1136\/bcr-2014-203682"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-203682","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,5,21]]}}}