{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:40:09Z","timestamp":1745757609531,"version":"3.40.4"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,4,20]]},"abstract":"<jats:p>The only proven therapy for glaucoma is intraocular pressure (IOP) reduction, which can be accomplished by different means. Each should be properly discussed with patients in order to best preserve visual function and quality of life. We report a case of unilateral pseudoexfoliative glaucoma, treated for years with triple topical IOP-lowering drugs. The patient presented with advanced optic neuropathy and important ocular side effects secondary to the treatment. Having discussed his options and prognosis, laser trabeculoplasty was performed while maintaining the remaining therapy considering the advanced stage of glaucoma. His IOP was effectively reduced and no progression was noted after 1-year follow-up. Although medical therapy is the mainstream in glaucoma management, its side effects should not be ignored, especially in unilateral cases. Surgery might have been a better solution, but we chose to perform laser trabeculoplasty, an effective and safer alternative, considering the unlikely but serious risk of the \u201cwipe-out phenomenon\u201d in this case.<\/jats:p>","DOI":"10.1136\/bcr-2014-204011","type":"journal-article","created":{"date-parts":[[2014,5,21]],"date-time":"2014-05-21T10:56:53Z","timestamp":1400669813000},"page":"bcr2014204011","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Managing advanced unilateral pseudoexfoliative glaucoma"],"prefix":"10.1136","volume":"2014","author":[{"given":"Andr\u00e9","family":"Marques","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,5,21]]},"reference":[{"key":"2025042705170321000_2014.may21_2.bcr2014204011.1","unstructured":"American Academy of Ophthalmology. Basic and Clinical Science Course 2011\u20132012, Section 10: Glaucoma."},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.2","doi-asserted-by":"crossref","unstructured":"Yanoff M Duker JS . Ophthalmology, 3rd edition. 2009. Part 10: Glaucoma.","DOI":"10.1016\/B978-0-323-04232-1.50021-9"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.3","doi-asserted-by":"crossref","unstructured":"Kanski JJ Bowling B . Clinical ophthalmology\u2014a systematic approach, 7th edition, 2011. Chapter 10 (pages 311\u2013400)\u2014Glaucoma.","DOI":"10.1016\/B978-0-7020-4093-1.00010-0"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.4","unstructured":"Rhee DJ . Wills Eye Institute Color Atlas and Synopsis of Clinical Ophthalmology\u2014Glaucoma, 2012."},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(87)33413-X"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(88)33190-8"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.7","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1327946"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.8","unstructured":"American Optometric Association. Optometric Clinical Practice Guideline\u2014Care of the Patient with Ocular Surface Disorders. 2011."},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.03.045"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.10","doi-asserted-by":"publisher","DOI":"10.3109\/09273948.2012.723106"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.11","doi-asserted-by":"publisher","DOI":"10.1586\/17512433.2.1.87"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.12","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31825af67d"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.13","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ajo.2005.04.016","article-title":"Risk of sudden visual loss following filtration surgery in end-stage glaucoma","volume":"140","author":"Topouzis","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.14","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.125.8.1044"},{"key":"2025042705170321000_2014.may21_2.bcr2014204011.15","first-page":"346","article-title":"Visual outcome and risk of sudden visual loss following trabeculectomy in end-stage glaucoma","volume":"22","author":"Chockalingam","year":"2010","journal-title":"Kerala Journal of Ophthalmology"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:17:12Z","timestamp":1745756232000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,21]]},"references-count":15,"alternative-id":["10.1136\/bcr-2014-204011"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204011","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,5,21]]}}}