{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:10:01Z","timestamp":1756293001221,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,6,13]]},"abstract":"<jats:p>A 13-year-old boy presented with fever, skeletal pain, polydipsia, polyuria and multiple osteolytic lesions in pelvic bones and upper femur. There was no organomegaly or lymphadenopathy. His serum calcium levels were raised. Peripheral blood film examination was normal. Bone marrow showed presence of blast cells. Flowcytometry indicated B-acute lymphoblastic leukaemia (B-ALL). Hypercalcaemia and osteolytic lesions are rare presentations of B-ALL. This should be kept as a differential if a child presents with unexplained skeletal pain with lytic lesions.<\/jats:p>","DOI":"10.1136\/bcr-2014-204050","type":"journal-article","created":{"date-parts":[[2014,7,8]],"date-time":"2014-07-08T11:00:47Z","timestamp":1404817247000},"page":"bcr2014204050","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["B-acute lymphoblastic leukaemia"],"prefix":"10.1136","volume":"2014","author":[{"given":"Rashmi","family":"Kushwaha","sequence":"first","affiliation":[{"name":"Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashutosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mili","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uma Shankar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology, KGMU, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,7,8]]},"reference":[{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.1","doi-asserted-by":"publisher","DOI":"10.5812\/iranjradiol.6765"},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.2","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/53260198"},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.3","first-page":"76","article-title":"Acute lymphoblastic leukemia without circulating blasts presenting as severe hypercalcemia","volume":"45","author":"Oloomi","year":"2007","journal-title":"Acta Medica Iranica"},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.4","first-page":"630","article-title":"Systemic lesions presenting as primary osteolytic lesions","volume":"110","author":"Sirelkhatim","year":"2009","journal-title":"Bratisl Lek Listy"},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.5","doi-asserted-by":"publisher","DOI":"10.4103\/2141-9248.113673"},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.6","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1055\/s-0041-1733232","article-title":"A child with acute lymphoblastic leukemia (ALL) presenting with symptomatic hypercalcemia and multiple osteolytic lesions","volume":"28","author":"Bhat","year":"2007","journal-title":"Indian J Med Paediatr Oncol"},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.7","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1002\/pbc.20357","article-title":"Acute lymphocytic leukemia in adolescence with multiple osteolytic lesions and hypercalcemia mediated by lymphoblast-producing parathyroid hormone-related peptide: a case report and review of the literature","volume":"3","author":"Shimonodan","year":"2005","journal-title":"Pediatric Blood Cancer."},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.8","first-page":"73","article-title":"Osteolytic bone lesions, hypercalcemia, and renal failure: a rare presentation of childhood acute lymphoblastic leukemia","volume":"1","author":"Peterson","year":"2013","journal-title":"Am J Cancer Case Rep"},{"key":"2025082703412327000_2014.jul08_1.bcr2014204050.9","doi-asserted-by":"publisher","DOI":"10.5045\/kjh.2007.42.4.433"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:41:30Z","timestamp":1756291290000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,8]]},"references-count":9,"alternative-id":["10.1136\/bcr-2014-204050"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204050","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,7,8]]}}}