{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:48:23Z","timestamp":1756460903583,"version":"3.40.4"},"reference-count":21,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,4,8]]},"abstract":"<jats:p>Cardiogenic flash pulmonary oedema is a common and potentially fatal cause of acute respiratory distress. Although it often results from acute decompensated heart failure, abrupt-onset aortic regurgitation can sharply rise cardiac filling pressure and, consequently, pulmonary venous pressure, leading to rapid fluid accumulation in the interstitial and alveolar spaces. We report a case of a 64-year-old woman admitted to the emergency department with a flash pulmonary oedema; a careful clinical investigation subsequently revealed a rare aetiology for this \u2018common\u2019 presentation. After a detailed auscultation that unmasked a diastolic cardiac murmur, an acute severe aortic insufficiency was further confirmed by echocardiography, showing inflammation and thickening of the entire aorta wall. The patient was submitted to valve replacement surgery, and histological examination, to our surprise, showed features of aortitis, remarkable for the presence of giant cells. A diagnosis of idiopathic aortitis versus inaugural giant cell arteritis was proposed and treatment started with corticosteroids.<\/jats:p>","DOI":"10.1136\/bcr-2014-204131","type":"journal-article","created":{"date-parts":[[2014,5,2]],"date-time":"2014-05-02T13:57:46Z","timestamp":1399039066000},"page":"bcr2014204131","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Pulmonary oedema in the emergency room: what is hidden beyond an apparently common presentation"],"prefix":"10.1136","volume":"2014","author":[{"given":"Catarina","family":"Patr\u00edcio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filipa Pais da","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edtor","family":"Brotas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,5,2]]},"reference":[{"key":"2025042703315052000_2014.apr30_3.bcr2014204131.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp052699"},{"key":"2025042703315052000_2014.apr30_3.bcr2014204131.2","unstructured":"Givertz MM Colucci WS Braunwald E . Clinical aspects of heart failure; pulmonary edema, high-output failure. In: Zipes DP Libby P Bonow RO Braunwald E . eds Heart disease: a textbook of cardiovascular medicine. 7th edn. 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Isolated (idiopathic) active aortitis in ascending aortic aneurysms: an underrecognized vasculitis. Rev Esp Patol 2012 ;45:175\u201380.","DOI":"10.1016\/j.patol.2011.11.004"},{"key":"2025042703315052000_2014.apr30_3.bcr2014204131.11","doi-asserted-by":"crossref","unstructured":"Hunder GG, Bloch DA, Michel BA, et al. The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum 1990;33:1122.","DOI":"10.1002\/art.1780330810"},{"key":"2025042703315052000_2014.apr30_3.bcr2014204131.12","doi-asserted-by":"crossref","unstructured":"Arend WP, Michel BA, Bloch DA, et al. The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. 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