{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:25:40Z","timestamp":1760898340613,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,9,26]]},"abstract":"<jats:p>Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign mesenchymal proliferative process, initially described by Vuitch <jats:italic>et al<\/jats:italic>. We report an unusual case of a 46-year-old woman who presented with a 6-week history of bilateral massive, asymmetrical, painful enlargement of her breasts, without a history of trauma. On clinical examination, both breasts were markedly enlarged and oedematous, but there were no discrete palpable masses. Preoperative image-guided core biopsies and surgery showed PASH. PASH is increasingly recognised as an incidental finding on image-guided core biopsy performed for screen detected lesions. There are a few reported cases of PASH presenting as rapid breast enlargement. In our case, the patient presented with painful, asymmetrical, massive breast enlargement. Awareness needs to be raised of this entity as a differential diagnosis in massive, painful breast enlargement.<\/jats:p>","DOI":"10.1136\/bcr-2014-204343","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T16:52:39Z","timestamp":1445014359000},"page":"bcr2014204343","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Pseudoangiomatous stromal hyperplasia causing massive breast enlargement"],"prefix":"10.1136","volume":"2015","author":[{"given":"Anita Geraldine","family":"Bourke","sequence":"first","affiliation":[{"name":"Department of Radiology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Tiang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Harvey","sequence":"additional","affiliation":[{"name":"Department of Pathwest, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"McClure","sequence":"additional","affiliation":[{"name":"Department of Pathwest, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,10,16]]},"reference":[{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(86)80292-1"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/modpathol.3801003","article-title":"Pseudoangiomatous stromal hyperplasia tumor: a clinical, radiologic and pathologic study of 26 cases","volume":"21","author":"Ferreira","year":"2008","journal-title":"Mod Pathol"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.3","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.51.3.204"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199503000-00004"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.5","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.5858\/2008-0686-RS.1","article-title":"Pseudoangiomatous stromal hyperplasia: an overview","volume":"134","author":"Virk","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.6","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890315)63:6<1154::AID-CNCR2820630619>3.0.CO;2-Q"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4741.2012.01230.x"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.8","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-007-3540-6"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.9","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199102000-00007"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.10","doi-asserted-by":"publisher","DOI":"10.2325\/jbcs.12.331"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.11","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2010.11.3.355"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2009.10.003"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.13","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.198.1.8539361"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.14","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2479"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.15","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-1170-5"},{"key":"2025082804293702000_2015.oct16_1.bcr2014204343.16","doi-asserted-by":"publisher","DOI":"10.1177\/1066896908320835"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:29:42Z","timestamp":1756380582000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,16]]},"references-count":16,"alternative-id":["10.1136\/bcr-2014-204343"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204343","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,10,16]]}}}