{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T07:50:19Z","timestamp":1764402619254,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,7,25]]},"abstract":"<jats:p>West-African trypanosomiasis caused by <jats:italic>Trypanosoma brucei gambiense<\/jats:italic> is a rare imported infection presenting with somnolence, lymphadenopathy and wide-ranging neurological symptoms. A 67-year-old Caucasian man presented with a 10-month history of cognitive deterioration, ataxic gait, somnolence and urinary incontinence. His symptoms had progressed more rapidly over the course of a month prior to admission. Serological testing confirmed a diagnosis of West-African trypanosomiasis. The patient was successfully treated with eflornithine and made a good recovery. West-African trypanosomiasis should be considered in the differential diagnosis of unexplained cognitive decline in those with a relevant travel history. If left untreated, the condition is universally fatal.<\/jats:p>","DOI":"10.1136\/bcr-2014-204451","type":"journal-article","created":{"date-parts":[[2014,8,14]],"date-time":"2014-08-14T09:41:38Z","timestamp":1408009298000},"page":"bcr2014204451","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["West-African trypanosomiasis in a returned traveller from Ghana: an unusual cause of progressive neurological decline"],"prefix":"10.1136","volume":"2014","author":[{"given":"Ivo","family":"Elliott","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Nottingham University Hospitals City Campus, Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trupti","family":"Patel","sequence":"additional","affiliation":[{"name":"Hospital for Tropical Diseases, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagrit","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nottingham University Hospitals, Nottingham, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradhib","family":"Venkatesan","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Nottingham University Hospitals City Campus, Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,8,14]]},"reference":[{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60829-1"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.2","first-page":"71","article-title":"Human African trypanosomiasis (sleeping sickness) epidemiological update","volume":"8","author":"World Health Organization","year":"2006","journal-title":"Wkly Epidemiol Rec"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.3","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00834-X"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.4","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.12-3-295"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-006-0093-3"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2010.02546.x"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001919"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.8","doi-asserted-by":"crossref","first-page":"947","DOI":"10.4269\/ajtmh.2009.80.947","article-title":"Magnetic resonance imaging findings in human African trypanosomiasis: a four year follow up study in a patient and review of the literature","volume":"80","author":"Kager","year":"2009","journal-title":"Am J Trop Med Hyg"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.9","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000209306.41647.13"},{"key":"2025082722323750000_2014.aug14_1.bcr2014204451.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61117-X"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:32:43Z","timestamp":1756359163000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,14]]},"references-count":10,"alternative-id":["10.1136\/bcr-2014-204451"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204451","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,8,14]]}}}