{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T10:36:02Z","timestamp":1787999762237,"version":"build-2784847793"},"reference-count":16,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,4,4]]},"abstract":"<jats:p>Infratentorial subdural empyema is a neurosurgical emergency that is associated with an alarmingly high morbidity and mortality if appropriate management is delayed. It is an important differential to consider when confronted with a patient with a reduced Glasgow Coma Scale, focal neurology and symptoms of raised intracranial pressure in the presence of a head and neck infection. It is also important that the primary team managing these patients is aware of the many pathogens that may be involved, including<jats:italic>Escherichia coli.<\/jats:italic>Early recognition, prompt diagnosis, timely involvement of the appropriate multidisciplinary teams, including neurosurgery, otorhinolaryngology, radiology and microbiology should be sought, and urgent intervention are imperative in avoiding a fatal outcome. This article presents a case of<jats:italic>E coli-<\/jats:italic>positive infratentorial subdural empyema secondary to mastoiditis due to underlying cholesteatoma, and a review of the pertinent literature.<\/jats:p>","DOI":"10.1136\/bcr-2014-204498","type":"journal-article","created":{"date-parts":[[2014,4,28]],"date-time":"2014-04-28T13:07:52Z","timestamp":1398690472000},"page":"bcr2014204498","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["<i>Escherichia coli<\/i>positive infratentorial subdural empyema secondary to mastoiditis and underlying cholesteatoma"],"prefix":"10.1136","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0406-2551","authenticated-orcid":false,"given":"Omar","family":"Mirza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Varadarajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir Saam","family":"Youshani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Willatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,4,28]]},"reference":[{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199712000-00005"},{"issue":"(5 Suppl)","key":"2025042703282403000_2014.apr28_2.bcr2014204498.2","first-page":"370","article-title":"Pediatric infratentorial subdural empyema: analysis of 14 cases","volume":"105","author":"Venkatesh","year":"2006","journal-title":"J Neurosurg"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.3","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.72.2.0299"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.4","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/108.4.983"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.5","first-page":"669","article-title":"Subtentorial subdural empyema: report of two cases and review of the literatures","volume":"21","author":"Taha","year":"2011","journal-title":"Turk Neurosurg"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.6","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.44.90"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.7","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199904000-00101"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1148\/radiology.155.2.3983389","article-title":"Acute otomastoiditis and its complications: role of CT","volume":"155","author":"Mafee","year":"1985","journal-title":"Radiology"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.9","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000266631.19745.32"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.10","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v1.i5.172"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.11","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.50.9.1136"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.12","first-page":"200","article-title":"Infratentorial subdural empyema","volume":"19","author":"Sengul","year":"2009","journal-title":"Turk Neurosur"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.13","doi-asserted-by":"publisher","DOI":"10.1148\/rg.232025076"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.14","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.78.4.0574"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.15","doi-asserted-by":"publisher","DOI":"10.4236\/crcm.2013.25079"},{"key":"2025042703282403000_2014.apr28_2.bcr2014204498.16","doi-asserted-by":"publisher","DOI":"10.1159\/000094065"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:28:34Z","timestamp":1745749714000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,28]]},"references-count":16,"alternative-id":["10.1136\/bcr-2014-204498"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204498","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,28]]}}}