{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:06:34Z","timestamp":1756382794657,"version":"3.40.4"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,5,14]]},"abstract":"<jats:p><jats:italic>Actinomyces meyeri<\/jats:italic>is a Gram-positive anaerobic forming bacterium of the genus<jats:italic>Actinomyces<\/jats:italic>, part of the oral cavity's flora, and its classification remains an unresolved issue. It is an extremely rare cause of disease, occurring in middle-aged immunocompetent patients and frequently misdiagnosed as malignancy or lung abscess. A 56-year-old man diagnosed with oesophageal squamous cell carcinoma had an endoscopically placed stent to palliate his dysphagia. Two weeks later he presented with thoracalgia and fever, interpreted as a common lung infection. Owing to lack of improvement, additional examinations were undertaken revealing mediastinum involvement. Unlike the good prognosis usually associated with this infection, the patient eventually died, reflecting the aggressive nature of his underlying condition. To our knowledge, this is the first report of mediastinitis by<jats:italic>A. meyeri<\/jats:italic>, supporting the described propensity of this agent to disseminate, particularly to the thoracic cavity, although probably in this case with an iatrogenic contribution.<\/jats:p>","DOI":"10.1136\/bcr-2014-204499","type":"journal-article","created":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T15:19:55Z","timestamp":1401981595000},"page":"bcr2014204499","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Mediastinitis by<i>Actinomyces meyeri<\/i>after oesophageal stent placement"],"prefix":"10.1136","volume":"2014","author":[{"given":"Diogo Ferreira","family":"Branquinho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Ramos","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Sofia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,6,5]]},"reference":[{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.1","unstructured":"Holdeman LV Cato EP Moore WE . Anaerobe laboratory manual. 4th edn. Blacksburg, VA: Virginia Polytechnic Institute and State University, 1977: 61\u20132."},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.2","unstructured":"Clinical and Laboratory Standards Institute. Interpretive criteria for identification of bacteria and fungi by DNA target sequencing: approved guideline . CLSI Document 18-A. Wayne, PA, 2008."},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2012.02.016"},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.5070\/D30N05580M","article-title":"Primary cutaneous actinomycosis caused by Actinomyces meyeri as first manifestation of HIV infection","volume":"17","author":"Gomes","year":"2011","journal-title":"Dermatol Online J"},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.5","doi-asserted-by":"publisher","DOI":"10.3201\/eid1803.111481"},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.6","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1183\/09031936.03.00089103","article-title":"Pulmonary actinomycosis","volume":"21","author":"Mabeza","year":"2003","journal-title":"Eur Respir J"},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.7","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.4.621"},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.8","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1155\/2011\/462608","article-title":"Pulmonary actinomycosis in a male patient with a tracheal bronchus","volume":"18","author":"Costiniuk","year":"2011","journal-title":"Can Respir J."},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.9","unstructured":"McNeil MM Schaal KP . Actinomyces species (Actinomycoses) Antimicrobial therapy and vaccines. Volume I: Microbes. 2nd edn. Antimicrobe. 2012."},{"key":"2025042705394702000_2014.jun05_1.bcr2014204499.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmedc.2008.08.003"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204499","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:39:57Z","timestamp":1745757597000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,5]]},"references-count":10,"alternative-id":["10.1136\/bcr-2014-204499"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204499","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,6,5]]}}}