{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T18:44:43Z","timestamp":1766515483572,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,6,17]]},"abstract":"<jats:p>Congenital ichthyosis includes a group of rare skin disorders known for tiles of hyperkeratotic skin resembling fish scales. With age, the hyperkeratosis generally becomes more concentrated around joints which increases impairment. Ichthyosis with confetti, also known as ichthyosis variegata or congenital reticular ichthyosiform erythroderma, is an extremely rare form of ichthyosis. It usually begins as non-bullous congenital ichthyosiform erythroderma with the expected scaling. However, with time patients develop widespread \u2018confetti-like\u2019 patches of healthy skin. The healthy skin reflects clonal expansion of \u2018normal\u2019 or reverted cells. Cell reversion has potential for future therapies using revertant stem cells. Controlling symptoms with emollients is the goal of treatment for ichthyosis since it has no cure.<\/jats:p>","DOI":"10.1136\/bcr-2014-204509","type":"journal-article","created":{"date-parts":[[2014,7,10]],"date-time":"2014-07-10T12:28:59Z","timestamp":1404995339000},"page":"bcr2014204509","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Ichthyosis with confetti: a rare diagnosis and treatment plan"],"prefix":"10.1136","volume":"2014","author":[{"given":"Myra C","family":"Long","sequence":"first","affiliation":[{"name":"Department of Family Medicine, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,7,10]]},"reference":[{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.11.020"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2006.01.003"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.3","first-page":"79","article-title":"Updated molecular genetics and pathogenesis of ichthyoses","volume":"73","author":"Akiyama","year":"2011","journal-title":"Nagoya J Med Sci"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.4","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21326"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.5","first-page":"23","article-title":"Harlequin ichthyosis: one survival case report","volume":"8","author":"Liou","year":"2001","journal-title":"Clin Neonatol"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.6","first-page":"349","article-title":"Ichthyoses: differential diagnosis and molecular genetics","volume":"16","author":"Oji","year":"2006","journal-title":"Eur J Dermatol"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.7","doi-asserted-by":"publisher","DOI":"10.1177\/0009922811430348"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.8","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.3.351"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.9","first-page":"577","article-title":"Ichthyoses\u2014part 2: congenital ichthyoses","volume":"7","author":"Krug","year":"2009","journal-title":"J Dtsch Dermatol Ges"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.10","doi-asserted-by":"publisher","DOI":"10.1126\/science.1192280"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10639.x"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.12","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310002684"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.13","first-page":"29","article-title":"Early immunopathological diagnosis of ichthyosis with confetti in two sporadic cases with new mutations in keratin 10","volume":"21","author":"Diociaiuti","year":"2014","journal-title":"Acta Derm Venereol"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.05.017"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.15","first-page":"511","article-title":"Ichthyoses\u2014part 1: differential diagnosis of vulgar ichthyoses and therapeutic options","volume":"7","author":"Krug","year":"2009","journal-title":"J Dtsch Dermatol Ges"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.16","first-page":"389","article-title":"Harlequin ichthyosis in an African child: case report","volume":"87","author":"Migowa","year":"2010","journal-title":"East Afr Med J"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.17","first-page":"599","article-title":"Treatment of congenital ichthyosis with acitretin: a case report","volume":"62","author":"Cakmak","year":"2010","journal-title":"Minerva Pediatr"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.18","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2009.100"},{"key":"2025082701581528000_2014.jul10_1.bcr2014204509.19","doi-asserted-by":"publisher","DOI":"10.1126\/science.1195991"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:58:23Z","timestamp":1756285103000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,10]]},"references-count":19,"alternative-id":["10.1136\/bcr-2014-204509"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204509","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,7,10]]}}}