{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T01:46:23Z","timestamp":1793065583019,"version":"4.5.0"},"reference-count":13,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,7,5]]},"abstract":"<jats:p>Brain abscess is an unusual complication of uncontrolled diabetes. A solitary thalamic abscess is an uncommon type of brain abscess. We report a case of thalamic abscess, whereupon diabetes mellitus and periodontitis were diagnosed. The diagnosis and management of thalamic abscess, and the interplay of type 2 diabetes and periodontitis are discussed. A 56-year-old, Caucasian, man with no medical or travel history, presented with 5-day symptoms of meningeal irritation. Body mass index 30.6\u2005kg\/m<jats:sup>2<\/jats:sup>. CT demonstrated a solitary midline lesion with neoplasia as a differential diagnosis. It was biopsied and cultures grew <jats:italic>Streptococcus milleri<\/jats:italic>. He was treated by stereotactic puncture, external drainage and targeted intrathecal and systemic antibiotic therapy. HIV negative but glycated haemoglobin (HbA1c) 10.7% (93\u2005mmol\/mol). Dental examination revealed a small molar abscess. Radiological resolution of the thalamic abscess occurred within 2\u2005months. Diabetes improved with 7\u2005weeks of insulin, and maintained on metformin, HbA1c 6.9% (51\u2005mmol\/mol). There was no residual neurological disability.<\/jats:p>","DOI":"10.1136\/bcr-2014-204654","type":"journal-article","created":{"date-parts":[[2014,7,22]],"date-time":"2014-07-22T02:34:59Z","timestamp":1405996499000},"page":"bcr2014204654","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Silent diabetes mellitus, periodontitis and a new case of thalamic abscess"],"prefix":"10.1136","volume":"2014","author":[{"given":"Ioannis","family":"Karageorgiou","sequence":"first","affiliation":[{"name":"Department of Medicine, King's College Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Chandler","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, King's College Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin Brunel","family":"Whyte","sequence":"additional","affiliation":[{"name":"Department of Diabetes, King's College Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,7,21]]},"reference":[{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.1","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-011-0086-5"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01808554"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.3","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1202360"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.4","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.33.630"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.5","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198410000-00005"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0899-7071(02)00436-9"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.7","first-page":"749","article-title":"A case of solitary thalamic abscess treated by sterotactic aspiration","volume":"42","author":"Yoritaka","year":"1990","journal-title":"No To Shinkei"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.8","doi-asserted-by":"publisher","DOI":"10.1086\/514658"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.9","doi-asserted-by":"publisher","DOI":"10.3109\/00365548809032427"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.10","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/00005792-198907000-00005","article-title":"Infections due to Lancefield Group C streptococci","volume":"68","author":"Salata","year":"1989","journal-title":"Medicine (Baltimore)"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.11","unstructured":"Guideline on oral health for people with diabetes 2009. International Diabetes Federation. http:\/\/www.idf.org\/webdata\/docs\/OralHealth_EN_RTP.pdf ."},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.12","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2013.1340011"},{"key":"2025082703173276000_2014.jul21_1.bcr2014204654.13","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12084"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:17:37Z","timestamp":1756289857000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,21]]},"references-count":13,"alternative-id":["10.1136\/bcr-2014-204654"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204654","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,21]]}}}