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The true diagnosis of CNS HS requires an extensive immunophenotypic workup using specific histiocytic markers, such as CD163, with the exclusion of markers of other cell lineages. This clinicopathological case report describes an improved approach towards the differential diagnosis of CNS HS.<\/jats:p>","DOI":"10.1136\/bcr-2014-204663","type":"journal-article","created":{"date-parts":[[2014,8,14]],"date-time":"2014-08-14T13:41:38Z","timestamp":1408023698000},"page":"bcr2014204663","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Isolated cranial nerve palsies may point to primary histiocytic sarcoma"],"prefix":"10.1136","volume":"2014","author":[{"given":"Antoine","family":"Moulignier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Mikol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7oise","family":"Heran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lionel","family":"Galicier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,8,14]]},"reference":[{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.1","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.53.1"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.2","doi-asserted-by":"crossref","first-page":"5019","DOI":"10.1182\/blood-2011-01-293050","article-title":"The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications","volume":"117","author":"Campo","year":"2001","journal-title":"Blood"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-2559.2002.01418.x","article-title":"Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases","volume":"41","author":"Pileri","year":"2002","journal-title":"Histopathology"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.4","doi-asserted-by":"crossref","first-page":"301","DOI":"10.5858\/2007-131-301-PCNSHS","article-title":"Primary central nervous system histiocytic sarcoma with relapse to mediastinum: a case report and review of the literature","volume":"131","author":"Cao","year":"2007","journal-title":"Arch Pathol Lab Med"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2010.07.002"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2012.02.009"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2011.10.023"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2011.01205.x"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.9","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcq244"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.10","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.2012.1092"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.11","doi-asserted-by":"publisher","DOI":"10.1007\/s10014-012-0123-z"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2012.11.002"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.13","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-7-127"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.14","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.11.1714"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.15","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1124021"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.16","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200111000-00004"},{"key":"2025042706181203000_2014.aug14_1.bcr2014204663.17","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000157940.80538.ec"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-204663","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T13:18:16Z","timestamp":1745759896000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-204663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,14]]},"references-count":17,"alternative-id":["10.1136\/bcr-2014-204663"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-204663","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,8,14]]}}}