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Endoscopy showed markedly hyperplastic gastric folds consistent with M\u00e9n\u00e9triers disease, confirmed histologically by gland dilation and gastric pit expansion. Intravenous cetuximab was prescribed for 12\u2005months, with clinical, biochemical and endoscopic improvement. However, 5\u2005weeks post cetuximab completion, there was relapse to 50% gastric coverage with M\u00e9n\u00e9triers. A discussion around gastrectomy was rejected by the patient. This is the first report of relapsing M\u00e9n\u00e9triers disease in a female patient with ESRF; we suggest that long-term cetuximab should be considered if a gastrectomy is declined.<\/jats:p>","DOI":"10.1136\/bcr-2014-204954","type":"journal-article","created":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T12:20:55Z","timestamp":1409574055000},"page":"bcr2014204954","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Disease recurrence following cetuximab completion and declining a gastrectomy: what next to manage M\u00e9n\u00e9triers disease?"],"prefix":"10.1136","volume":"2014","author":[{"given":"Mitesh","family":"Patel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Mottershead","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,9,1]]},"reference":[{"key":"2025042706251462000_2014.sep01_1.bcr2014204954.1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.220061"},{"key":"2025042706251462000_2014.sep01_1.bcr2014204954.2","first-page":"32","article-title":"Des polyadenomes gastriques et de leur rapports avec le cancer l'estomac","volume":"1","author":"Menetrier","year":"1888","journal-title":"Arch Physiol Norm Pathol"},{"key":"2025042706251462000_2014.sep01_1.bcr2014204954.3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.46.1.395"},{"key":"2025042706251462000_2014.sep01_1.bcr2014204954.4","doi-asserted-by":"crossref","unstructured":"Anderson DK . 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