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Rituximab was well tolerated and allowed complete withdrawal of previous immunosuppression with steroids and azathioprine. The patient was in sustained remission up to month 32, when she experienced a relapse. A second infusion of rituximab (375\u2005mg\/m<jats:sup>2<\/jats:sup>) achieved prompt proteinuria reduction with no additional immunosuppressants. At 48\u2005months after the initial treatment, this patient is in complete remission without any immunosuppression. This case suggests that rituximab, even a single dose, may safely promote NS remission in adults with refractory FSGS.<\/jats:p>","DOI":"10.1136\/bcr-2014-205507","type":"journal-article","created":{"date-parts":[[2014,8,25]],"date-time":"2014-08-25T10:37:57Z","timestamp":1408963077000},"page":"bcr2014205507","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Refractory focal segmental glomerulosclerosis in the adult: complete and sustained remissions of two episodes of nephrotic syndrome after a single dose of 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