{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:43:44Z","timestamp":1756385024246,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,9,18]]},"abstract":"<jats:p>Good's syndrome is a rare primary immunodeficiency associated with adult thymoma. Complications are mainly autoimmune manifestations and recurrent infections with encapsulated bacteria. Only one possible case of combined granulomatous-lymphocytic interstitial lung disease (GL-ILD) and Good's syndrome have been described earlier, but the patient died at the time of diagnosis. This is the first case of GL-ILD in Good's syndrome with a successful outcome. We present a case of a 43-year-old man with GL-ILD, who suffered from recurrent infections of <jats:italic>Haemophilus influenzae<\/jats:italic> and <jats:italic>Pneumocystis jirovecii<\/jats:italic>, with 8-year follow-up. After a thymectomy, he was diagnosed with Good's syndrome and GL-ILD. He was treated with prophylactic pivampicillin, quinolones and cephalosporins for his recurrent <jats:italic>P. jirovecii<\/jats:italic> and <jats:italic>H. influenzae<\/jats:italic> infections, an approach that proved unsuccessful due to resistance, with relapse after cessation. He was stabilised with oral diaminodiphenyl-sulfone for <jats:italic>P. jirovecii<\/jats:italic> and colistimethate-sodium inhalations for <jats:italic>H. influenzae<\/jats:italic>, which is a new approach to prophylactic treatment.<\/jats:p>","DOI":"10.1136\/bcr-2014-205635","type":"journal-article","created":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T04:23:02Z","timestamp":1443586982000},"page":"bcr2014205635","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Granulomatous-lymphocytic interstitial lung disease and recurrent sinopulmonary infections in a patient with Good\u2019s syndrome"],"prefix":"10.1136","volume":"2015","author":[{"given":"Mads Lynge","family":"Jensen","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Bendstrup","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole","family":"Hilberg","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,9,30]]},"reference":[{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2010.01.006"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.2","first-page":"56","article-title":"Case report and literature review on Good's syndrome, a form of acquired immunodeficiency associated with thymomas","volume":"72","author":"Joven","year":"2013","journal-title":"Hawaii J Med Public Health"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.3","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.51.7028"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.4","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2008.23.4.219"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.5","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0025-7125(16)32278-7","article-title":"Diffuse pulmonary lymphoreticular infiltrations associated with dysproteinaemia","volume":"57","author":"Liebow","year":"1973","journal-title":"Med Clin North Am"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.05.057"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.7","first-page":"31","article-title":"Primary hypogammaglobulinaemia: a survey of clinical manifestations and complications","volume":"86","author":"Hermaszewski","year":"1993","journal-title":"Q J Med"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2009.10.002"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.9","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0b013e3283642c47"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(03)00042-8"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.11","doi-asserted-by":"publisher","DOI":"10.4103\/0022-3859.118040"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.12","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(06)70580-1"},{"key":"2025082805132044000_2015.sep30_1.bcr2014205635.13","doi-asserted-by":"crossref","unstructured":"Green H , Paul M , Vidal L , et al . 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