{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:02:03Z","timestamp":1756461723585,"version":"3.40.4"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,10,8]]},"abstract":"<jats:p>Mesenteric vein thrombosis is a rare but potentially lethal cause of abdominal pain. It is usually caused by prothrombotic states that can either be hereditary or acquired. Testosterone supplementation causes an acquired prothrombotic state by promoting erythropoeisis thus causing a secondary polycythaemia. We report a case of a 59-year-old man with a history of chronic obstructive pulmonary disease (COPD) stage III, who presented with abdominal pain. Evaluation revealed an elevated haemoglobin and haematocrit, a superior mesenteric vein thrombosis on CT and a negative Janus kinase 2 mutation. The patient is currently being treated with 6\u2005months of anticoagulation with rivaroxiban. Although a well-known side effect of testosterone is thrombosis, the present case is used to document in the literature the first case of mesenteric vein thrombosis due to secondary polycythaemia from Androgel in the setting of COPD.<\/jats:p>","DOI":"10.1136\/bcr-2014-206023","type":"journal-article","created":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T10:19:11Z","timestamp":1413886751000},"page":"bcr2014206023","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Mesenteric vein thrombosis caused by secondary polycythaemia from AndroGel"],"prefix":"10.1136","volume":"2014","author":[{"given":"Heather","family":"Katz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Popov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Bray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry","family":"Berman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,10,21]]},"reference":[{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.1","first-page":"285","article-title":"Mesenteric venous thrombosis","volume":"88","author":"Singal","year":"2013","journal-title":"Vasc Med"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.2","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X10379673"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.3","first-page":"1537","article-title":"Diagnosis of acute abdominal pain in older patients","volume":"74","author":"Lyon","year":"2006","journal-title":"Am Fam Physician"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.4","doi-asserted-by":"crossref","first-page":"495863","DOI":"10.1155\/2009\/495863","article-title":"Drug-induced hematologic syndromes","volume":"2009","author":"Mintzer","year":"2009","journal-title":"Adv Hematol"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.5","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.124197"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.6","first-page":"397","article-title":"Safety and efficacy of testosterone gel in the treatment of male hypogonadism","volume":"4","author":"Lakshman","year":"2009","journal-title":"Clin Interv Aging"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2004.01933.x"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.8","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1692"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.9","first-page":"199","article-title":"Hypoxemia in patients with COPD: cause, effects, and disease progression","volume":"6","author":"Kent","year":"2011","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.10","doi-asserted-by":"publisher","DOI":"10.1159\/000194888"},{"key":"2025042706480299000_2014.oct21_1.bcr2014206023.11","doi-asserted-by":"publisher","DOI":"10.1177\/1076029612460425"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-206023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T13:48:08Z","timestamp":1745761688000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-206023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,21]]},"references-count":11,"alternative-id":["10.1136\/bcr-2014-206023"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-206023","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2014,10,21]]}}}