{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:04:21Z","timestamp":1756425861828,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,10,23]]},"abstract":"<jats:p>Adrenocortical carcinoma is an aggressive cancer, with an incidence of 0.5\u20132 per million. We present a case of adrenocortical carcinoma with all the clinical and partly immunohistochemical features of disseminated undifferentiated lung cancer, and \u2018accidentally\u2019 treated as such. Four cycles of carboplatin\u2013vinorelbine conferred partial response in the adrenal, lung and disappearance of a 2\u2005cm subcutaneous iliac nodule that had appeared suddenly before the first course. Owing to progression, four cycles of carboplatin\u2013pemetrexed were administered inducing partial response and then stable disease for an additional 12\u2005months. As fluoro-<jats:sc>d<\/jats:sc>-glucose (FDG)-positron emission tomography (PET) only showed activity in the adrenal, laparoscopic adrenalectomy was performed. Three months later FDG-PET revealed a lung nodule unresponsive to carboplatin\u2013pemetrexed, removed by wedge resection. Finally, re-evaluation by a tertiary centre confirmed adrenocortical carcinoma with Ki67\u201450% in the adrenal and the lung. The patient is alive and tumour free almost 3.5\u2005years after retrospective diagnosis of metastatic adrenocortical cancer.<\/jats:p>","DOI":"10.1136\/bcr-2014-206225","type":"journal-article","created":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T04:57:49Z","timestamp":1415768269000},"page":"bcr2014206225","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Adrenocortical carcinoma mimicking lung cancer and responding to vinorelbine\/carboplatin and pemetrexed\/carboplatin"],"prefix":"10.1136","volume":"2014","author":[{"given":"Oluf Dimitri","family":"R\u00f8e","sequence":"first","affiliation":[{"name":"Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"Cancer Clinic, Levanger Hospital, Nord-Tr\u00f8ndelag Health Trust, Levanger, Norway"},{"name":"Department of Oncology, Aalborg University Hospital, Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per Arne","family":"Oppegaard","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Levanger Hospital, Levanger, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona-Elisabeth","family":"Revheim","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aud","family":"Svindland","sequence":"additional","affiliation":[{"name":"Department of Pathology, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,11,12]]},"reference":[{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.1","doi-asserted-by":"crossref","first-page":"234726","DOI":"10.1155\/2012\/234726","article-title":"Adrenocortical carcinoma: current therapeutic state-of-the-art","volume":"2012","author":"Lebastchi","year":"2012","journal-title":"J Oncol"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.2","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0b013e3283602274"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.3","doi-asserted-by":"publisher","DOI":"10.1097\/PAI.0b013e31828a96cf"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2012.04403.x"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.5","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.48.0988"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.6","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.229"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1973.03220100011003"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa063360"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200966"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-2042.2003.00651.x"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.11","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e31829e3221"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.12","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-1116-y"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.13","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds231"},{"key":"2025082804211234000_2014.nov12_1.bcr2014206225.14","unstructured":"Lack EE. 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