{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:40:07Z","timestamp":1756359607335,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,9,28]]},"abstract":"<jats:p>A 44-year-old Indian national with a prostate-specific antigen of 5.4\u2005ng\/mL underwent 12-core transrectal ultrasound-guided prostate biopsies. Following this, he had three hospital admissions with severe urosepsis secondary to extended spectrum \u03b2 lactamase (ESBL) producing <jats:italic>Escherichia coli<\/jats:italic>. He had recurrent sepsis immediately after discontinuation of intravenous meropenem to which the ESBL was sensitive. He proceeded to radical prostatectomy for intermediate-high risk Gleason 7 prostate cancer, while still on intravenous meropenem, 2\u2005months after his biopsy. His prostatectomy involved a difficult dissection due to inflammatory changes and fibrosis after multiple septic episodes. He had complete resolution of infection after surgery with discontinuation of antibiotics on the third postoperative day, without any recurrence of sepsis.<\/jats:p>","DOI":"10.1136\/bcr-2014-206291","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T06:44:08Z","timestamp":1413269048000},"page":"bcr2014206291","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Radical prostatectomy in the presence of ongoing refractory ESBL <i>Escherichia coli<\/i> bacterial prostatitis"],"prefix":"10.1136","volume":"2014","author":[{"given":"Louise Catherine","family":"McLoughlin","sequence":"first","affiliation":[{"name":"Tallaght Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T E D","family":"McDermott","sequence":"additional","affiliation":[{"name":"Tallaght Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John Alan","family":"Thornhill","sequence":"additional","affiliation":[{"name":"Tallaght Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,10,14]]},"reference":[{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/bju.12536","article-title":"Sepsis and \u2018superbugs\u2019: should we favour the transperineal over the transrectal approach for prostate biopsy?","volume":"114","author":"Grummet","year":"2014","journal-title":"BJU Int"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.06.003"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.11.015"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10561.x"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.5","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit193"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.6","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq471"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.7","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7796.109993"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.03.033"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.9","doi-asserted-by":"crossref","first-page":"650858","DOI":"10.1100\/2012\/650858","article-title":"Prospective study of antibiotic prophylaxis for prostate biopsy involving >1100 men","volume":"2012","author":"Manecksha","year":"2012","journal-title":"Sci World J"},{"key":"2025082722094647000_2014.oct14_1.bcr2014206291.10","doi-asserted-by":"crossref","unstructured":"Zani EL , Clark OA , Rodrigues Netto N Jr . 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