{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T02:26:46Z","timestamp":1767925606956,"version":"3.49.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,10,23]]},"abstract":"<jats:p>A 70-year-old man (case 1) and a 64-year-old woman (case 2) with multiple system atrophy (MSA) and snoring were admitted for polysomnography. Their awake PaCO<jats:sub>2<\/jats:sub>indicated normocapnia. Apnoea\u2013hypopnoea index (AHI), max transcutaneous carbon dioxide partial pressure (PtcCO<jats:sub>2<\/jats:sub>) and \u0394PtcCO<jats:sub>2<\/jats:sub>(max PtcCO<jats:sub>2<\/jats:sub>(during sleep)\u2014baseline PtcCO<jats:sub>2<\/jats:sub>(while awake)) were 11.4\/h, 63\u2005mm\u2005Hg and 18\u2005mm\u2005Hg, respectively, in case 1 and 53.1\/h, 59\u2005mm\u2005Hg and 13\u2005mm\u2005Hg, respectively, in case 2. Their sleep-disordered breathing (SDB) was diagnosed as obstructive sleep apnoea with hypoventilation. We thought that variable expiratory positive airway pressure and pressure support ventilation (advanced-adaptive servo ventilation (ASV)) might be favourable for their SDB. Polysomnography after introducing advanced-ASV revealed that AHI, max PtcCO<jats:sub>2<\/jats:sub>and \u0394PtcCO<jats:sub>2<\/jats:sub>were 0.2\/h, 53\u2005mm\u2005Hg and 5\u2005mm\u2005Hg, respectively, in case 1 and 1.5\/h, 56\u2005mm\u2005Hg and 9\u2005mm\u2005Hg, respectively, in case 2. Advanced-ASV for treating Cheyne-Stokes breathing may be helpful in SDB in patients with MSA.<\/jats:p>","DOI":"10.1136\/bcr-2014-206372","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T11:07:20Z","timestamp":1446808040000},"page":"bcr2014206372","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Use of a new generation of adaptive servo ventilation for sleep-disordered breathing in patients with multiple system atrophy"],"prefix":"10.1136","volume":"2015","author":[{"given":"Satoshi","family":"Hamada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiaki","family":"Mishima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Chin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,11,6]]},"reference":[{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.1","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-012-0189-2"},{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.2","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8257(200007)15:4<699::AID-MDS1015>3.0.CO;2-L"},{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.3","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70022-4"},{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2004.10.002"},{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2006.03.008"},{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.6","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.5665\/sleep.1438","article-title":"The performance of two automatic servo-ventilation devices in the treatment of central sleep apnea","volume":"34","author":"Javaheri","year":"2011","journal-title":"Sleep"},{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.7","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000324625.00404.15"},{"key":"2025042707343926000_2015.nov05_2.bcr2014206372.8","doi-asserted-by":"crossref","unstructured":"Donaldson I , Marsden CD , Schneider SA , et al . 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