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Over the next few days, however, the patient developed severe thirst and polyuria exceeding 6\u2005L of urine per day, accompanied by hypernatraemia and hypo-osmolar urine. She was presumed to have CDI due to NS, and intranasal desmopressin was administered. This eventually normalised her urine output and serum sodium. The patient was discharged improved on intranasal desmopressin and oral prednisone. AI may mask the manifestation of CDI because low serum cortisol impairs renal-free water clearance. Steroid replacement reverses this process and unmasks an underlying CDI.<\/jats:p>","DOI":"10.1136\/bcr-2014-206390","type":"journal-article","created":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T10:35:30Z","timestamp":1421922930000},"page":"bcr2014206390","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Neurosarcoidosis-associated central diabetes insipidus masked by adrenal insufficiency"],"prefix":"10.1136","volume":"2015","author":[{"given":"Lemuel","family":"Non","sequence":"first","affiliation":[{"name":"Department of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Brito","sequence":"additional","affiliation":[{"name":"Department of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Anastasopoulou","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Albert Einstein Medical Center, Elkins Park, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,1,22]]},"reference":[{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e31815585aa"},{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcs121"},{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.3","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg103"},{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.4","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e3181c92a72"},{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.5","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.214.2.r00fe05411"},{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.6","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-1981"},{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.7","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.73.1.65"},{"key":"2025082803311932000_2015.jan22_1.bcr2014206390.8","unstructured":"Shapiro M , Weiss JP . 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