{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T05:39:34Z","timestamp":1775021974483,"version":"3.50.1"},"reference-count":19,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,9,28]]},"abstract":"<jats:p>A 57-year-old man with symptoms of fatigue, joint pains and insomnia was found to have hypercalcaemia secondary to hyperparathyroidism with a corrected calcium of 2.61\u2005mmol\/L (2.2\u20132.6\u2005mmol\/L) and a serum parathyroid hormone (PTH) of 86\u2005pg\/mL (10\u201365\u2005pg\/mL). Preoperative workup demonstrated a parathyroid adenoma in the right upper position and he proceeded to surgery. Postoperatively, however, his symptoms remained unchanged and the corrected calcium remained elevated at 2.87\u2005mmol\/L with a PTH of 59\u2005pg\/mL. He had no family history of hypercalcaemia. Further investigations revealed low 24\u2005h urinary calcium level and a low urine calcium to creatinine ratio. Genetic testing revealed a mutation in exon 4 of the calcium sensing receptor (CaSR) confirming a diagnosis of familial hypocalciuric hyercalcaemia (FHH).<\/jats:p>\n               <jats:p>The case is an example of a rare phenomenon when a parathyroid adenoma develops in patients with FHH.<\/jats:p>","DOI":"10.1136\/bcr-2014-206473","type":"journal-article","created":{"date-parts":[[2014,10,15]],"date-time":"2014-10-15T07:07:30Z","timestamp":1413356850000},"page":"bcr2014206473","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":18,"title":["Parathyroid adenoma in a patient with familial hypocalciuric hypercalcaemia"],"prefix":"10.1136","volume":"2014","author":[{"given":"Hannah Elizabeth","family":"Forde","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Beaumont Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnold 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