{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T10:35:41Z","timestamp":1756895741059,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,3,10]]},"abstract":"<jats:p>Community-acquired methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (CA-MRSA) is a rare cause of necrotising fasciitis (NF), and is usually not fulminant as in group A <jats:italic>Streptococcus<\/jats:italic> (GAS), the archetypal aetiology. We report an unusually fulminant case of NF by CA-MRSA in an immunocompetent patient. A 52-year-old man presented to the emergency department with 1\u2005week of progressive left thigh pain and swelling. The patient had ecchymoses, bullae and hypoesthesia of the involved skin, and CT scan revealed extensive fascial oedema. He was immediately started on broad spectrum antibiotics. Within 12\u2005h of presentation, he underwent surgical debridement. Despite aggressive supportive care, the patient died less than 24\u2005h after presentation. MRSA, with an antibiogram suggestive of a community-acquired strain, was recovered from intraoperative specimens and admission blood cultures. This case underscores that CA-MRSA, while rarely reported, can cause a fulminant presentation of NF similar to GAS in immunocompetent patients.<\/jats:p>","DOI":"10.1136\/bcr-2014-206848","type":"journal-article","created":{"date-parts":[[2015,3,30]],"date-time":"2015-03-30T10:50:43Z","timestamp":1427712643000},"page":"bcr2014206848","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Fulminant necrotising fasciitis by community-acquired methicillin-resistant <i>Staphylococcus aureus<\/i>"],"prefix":"10.1136","volume":"2015","author":[{"given":"Lemuel","family":"Non","sequence":"first","affiliation":[{"name":"Department of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Kosmin","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,3,30]]},"reference":[{"key":"2025082722501296000_2015.mar30_1.bcr2014206848.1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1177\/000313480206800201","article-title":"Necrotizing fasciitis: a fourteen-year retrospective study of 163 consecutive patients","volume":"68","author":"Childers","year":"2002","journal-title":"Am Surg"},{"key":"2025082722501296000_2015.mar30_1.bcr2014206848.2","doi-asserted-by":"publisher","DOI":"10.1086\/533590"},{"key":"2025082722501296000_2015.mar30_1.bcr2014206848.3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00081-09"},{"key":"2025082722501296000_2015.mar30_1.bcr2014206848.4","doi-asserted-by":"crossref","unstructured":"Fridkin S , Hageman J , Morrison M , et al . 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