{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T03:24:21Z","timestamp":1784604261431,"version":"3.55.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,11,21]]},"abstract":"<jats:p>We present a case of Marfan syndrome with lens coloboma in one eye and ectopia lentis in the other. A 14-year-old girl reported decreased vision in the left eye. Her visual acuity was 6\/24 and counting fingers at 1\u2005m in the right and left eyes, respectively. Her intraocular pressure was 15\u2005mm\u2005Hg in both eyes. Evaluation of the right eye on slit lamp biomicroscopy under mydriasis revealed an inferiorly visible flattened and concave crystalline lens equator from 4 to 8 o\u2019clock position along with notching and absence of zonules, suggestive of lens coloboma. Left eye examination revealed a superiorly subluxated lens from 3 to 9 o'clock position and posterior subcapsular cataract. The posterior segment evaluation of both eyes was normal. Her father, aunt and grandfather were of tall stature, characteristic of Marfan syndrome. On systemic evaluation, the patient was diagnosed as Marfan syndrome. After surgical correction she achieved vision of 6\/6 in both eyes.<\/jats:p>","DOI":"10.1136\/bcr-2014-207112","type":"journal-article","created":{"date-parts":[[2014,12,10]],"date-time":"2014-12-10T07:54:35Z","timestamp":1418198075000},"page":"bcr2014207112","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Lens coloboma in one eye and ectopia lentis in the other eye of a patient with Marfan syndrome"],"prefix":"10.1136","volume":"2014","author":[{"given":"Bikram Bahadur","family":"Thapa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramandeep","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagat","family":"Ram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abiraj","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,12,9]]},"reference":[{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01204333"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.2","first-page":"179","article-title":"Ocular features of Marfan syndrome: diagnosis and management","volume":"10","author":"Nahum","year":"2008","journal-title":"Isr Med Assoc J"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.3","first-page":"21","article-title":"Coloboma of lens","volume":"32","author":"Angra","year":"1984","journal-title":"Indian J Ophthalmol"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.4","first-page":"201","article-title":"Bilateral coloboma of lens in Marfan's syndrome","volume":"33","author":"Mehrotra","year":"1985","journal-title":"Indian J Ophthalmol"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.5","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19960424)62:4<417::AID-AJMG15>3.0.CO;2-R"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2013.12.004"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.7","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e32835a939f"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2013.09.005"},{"key":"2025042707064648000_2014.dec09_1.bcr2014207112.9","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20120221-01"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-207112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:06:54Z","timestamp":1745762814000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-207112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,9]]},"references-count":9,"alternative-id":["10.1136\/bcr-2014-207112"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-207112","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,9]]}}}