{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:30:50Z","timestamp":1789576250708,"version":"build-2803163510"},"reference-count":16,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2014,12,6]]},"abstract":"<jats:p>Granulocytic sarcoma, also known as myeloid sarcoma, is an extramedullary tumour composed of immature myeloid cells. Granulocytic sarcoma is typically found in patients with acute myeloid leukaemia, accelerated phase or blast crisis of chronic myeloid leukaemia, myelodysplastic syndrome, or as an isolated event without bone marrow involvement. We present a case of granulocytic sarcoma in a patient with chronic myeloid leukaemia in the setting of complete haematological, molecular and cytogenetic remission. Our patient was first treated with imatinib for chronic-phase chronic myeloid leukaemia. After maintaining remission for 42\u2005months, he developed a granulocytic sarcoma in his spine. In this case report, we describe our case, along with the three other cases reported in the literature. In addition to being a rare diagnosis, this case demonstrates the importance of being vigilant in diagnosing the cause of back pain and atypical symptoms in patients with a history of leukaemia.<\/jats:p>","DOI":"10.1136\/bcr-2014-207466","type":"journal-article","created":{"date-parts":[[2014,12,23]],"date-time":"2014-12-23T12:50:16Z","timestamp":1419339016000},"page":"bcr2014207466","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Granulocytic sarcoma in a patient with chronic myeloid leukaemia in complete haematological, cytogenetic and molecular remission"],"prefix":"10.1136","volume":"2014","author":[{"given":"Adam","family":"Kittai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Mi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imad","family":"Tabbara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,12,23]]},"reference":[{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-347229"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.2","doi-asserted-by":"publisher","DOI":"10.1080\/10428190600967196"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.3","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1200\/JCO.1995.13.7.1800","article-title":"Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: a clinical review","volume":"13","author":"Byrd","year":"1995","journal-title":"J Clin Oncol"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.4","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1200\/JCO.1986.4.6.912","article-title":"Isolated granulocytic sarcoma: report of a case and review of the literature","volume":"4","author":"Eshghabadi","year":"1986","journal-title":"J Clin Oncol"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.5","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1200\/JCO.1993.11.4.690","article-title":"Granulocytic sarcoma is associated with the 8;21 translocation in acute myeloid leukemia","volume":"11","author":"Tallman","year":"1993","journal-title":"J Clin Oncol"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.6","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-123-5-199509010-00005"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2013.04.012"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00277-002-0569-x","article-title":"Extramedullary blast crisis of chronic myeloid leukemia after allogeneic hematopoietic stem cell transplantation mimicking aggressive, translocation t(14;18)-positive B-cell lymphoma","volume":"82","author":"Kroschinsky","year":"2003","journal-title":"Ann Hematol"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.9","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.1998.13.4.434"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2257.2006.00782.x"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-05-1816"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.12","doi-asserted-by":"publisher","DOI":"10.1532\/IJH97.04188"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.13","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-03-380147"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.14","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.6315"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.15","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.041418"},{"key":"2025042707110007000_2014.dec23_1.bcr2014207466.16","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404491"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-207466","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:11:08Z","timestamp":1745763068000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-207466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,23]]},"references-count":16,"alternative-id":["10.1136\/bcr-2014-207466"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-207466","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,23]]}}}