{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:26:53Z","timestamp":1784172413213,"version":"3.55.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,8,3]]},"abstract":"<jats:p>We describe the clinical outcomes of two contrasting cases of fungal keratitis due to<jats:italic>Paecilomyces<\/jats:italic>spp. The first case involving a 58-year-old woman was complicated by an initial laboratory misidentification as<jats:italic>Penicillium<\/jats:italic>and consequently a delay in treatment with an optimised antifungal regimen. The patient had a protracted clinical course that required a total of four penetrating keratoplasties. However, an accurate diagnosis was promptly made in the second case, a 46-year-old woman, which resulted in a satisfactory outcome after penetrating keratoplasty. Our principal aim was to highlight a diagnostic challenge relating to the accurate microbial identification of<jats:italic>Paecilomyces<\/jats:italic>spp. This can be difficult given its morphological similarity to<jats:italic>Pencillium<\/jats:italic>, and confusion over the two genera has resulted in misdiagnoses reported previously. Our report aims to raise awareness of this potential laboratory misidentification, which can affect clinical decision-making in guiding antimicrobial therapy.<\/jats:p>","DOI":"10.1136\/bcr-2014-207605","type":"journal-article","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T15:39:59Z","timestamp":1439912399000},"page":"bcr2014207605","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["A masquerader?<i>Paecilomyces<\/i>must be distinguished from<i>Penicillium<\/i>in fungal keratitis: a report of two contrasting cases"],"prefix":"10.1136","volume":"2015","author":[{"given":"Arsham","family":"Sheybani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander T","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Harocopos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J","family":"Lubniewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J W","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,8,18]]},"reference":[{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.11.027"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01481.x"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.11.016"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.09.011"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1536(57)80066-7"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.6","first-page":"58","article-title":"Paecilomyces and some allied hyphomycetes","volume":"6","author":"Samson","year":"1974","journal-title":"Stud Mycol"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0691.2001.00054.x"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.8","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.1.262-268.2006"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.9","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000114126.63670.4f"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.10","doi-asserted-by":"publisher","DOI":"10.1080\/00362177985380541"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.11","doi-asserted-by":"publisher","DOI":"10.1080\/00362178585380421"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.12","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181af7626"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.13","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000230497.99648.8d"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.14","doi-asserted-by":"publisher","DOI":"10.1086\/516136"},{"key":"2025042706583124000_2015.aug18_1.bcr2014207605.15","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF00158578","article-title":"In vitro sensitivity of Penicillium marneffei and Pythium insidiosum to various antifungal agents","volume":"3","author":"Sekhon","year":"1992","journal-title":"Eur J Epidemiol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-207605","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T13:58:39Z","timestamp":1745762319000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-207605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,18]]},"references-count":15,"alternative-id":["10.1136\/bcr-2014-207605"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-207605","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,18]]}}}