{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:40:22Z","timestamp":1756294822643,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,5,25]]},"abstract":"<jats:p>We present a case of adverse neurological effects of methylphenidate therapy for attention deficit and hyperactivity disorder (ADHD). A 7-year-old boy presented to the emergency department (ED) having developed ataxic gait, orofacial dyskinesias and choreoathetosis of the limbs. The results of all blood investigations, EEG and CT scan of the head were unremarkable. Subsequently, a detailed history revealed he was being treated for ADHD, being started on methylphenidate in the past 3\u2005months. Discontinuation of methylphenidate led to significant and rapid amelioration of neurological adverse effects.<\/jats:p>","DOI":"10.1136\/bcr-2014-207796","type":"journal-article","created":{"date-parts":[[2015,6,16]],"date-time":"2015-06-16T09:29:48Z","timestamp":1434446988000},"page":"bcr2014207796","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Neurological adverse effects of methylphenidate may be misdiagnosed as meningoencephalitis"],"prefix":"10.1136","volume":"2015","author":[{"given":"Luke Blagdon","family":"Snell","sequence":"first","affiliation":[{"name":"Royal Free London NHS Trust, London, UK"},{"name":"Medical School, UCL, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinkar","family":"Bakshi","sequence":"additional","affiliation":[{"name":"East & North Hertfordshire Hospitals NHS Trust, Welwyn Garden City, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,6,16]]},"reference":[{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2089O"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-2654"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.3","first-page":"615","article-title":"The changing prevalence of attention deficit\/hyperactivity disorder and methylphenidate prescriptions: a study of data from a random sample of insurees of the AOK Health Insurance Company in the German State of Hesse, 2000\u20132007","volume":"107","author":"Schubert","year":"2010","journal-title":"Dtsch Arztebl Int"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.4","doi-asserted-by":"crossref","unstructured":"Factor SA , Lang AE , Weiner WJ . Movement disorders and dopaminomimetic stimulant drugs. In: Munson AE , Sanchez-Ramos J , Weiner WJ, eds . Drug induced movement disorders. 2nd edn. Oxford, Wiley-Blackwell, 2005:351\u201367. Chapter 14.","DOI":"10.1002\/9780470753217.ch14"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.5","unstructured":"Committee on Medicinal Products for Human Use (CHMP). Elements recommended for inclusion in Summaries of Product Characteristics for methylphenidate-containing medicinal products authorised for the treatment of ADHD in children aged six years and above and adolescents. 2009. Available at: www.ema.europa.eu (accessed 03 Jun 2015)."},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.6","doi-asserted-by":"publisher","DOI":"10.4088\/PCC.v04n0408a"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.7","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.135.2.252"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.8","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-197407000-00006"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1542\/peds.53.2.236","article-title":"Dextroamphetamine and methylphenidate in the treatment of hyperactive-aggressive children","volume":"53","author":"Winsberg","year":"1974","journal-title":"Pediatrics"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1968.03140180050018"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2013.01.008"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.12","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2000.10.39"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(02)00429-0"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.14","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2006.0055"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.15","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199511000-00016"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.16","doi-asserted-by":"publisher","DOI":"10.1177\/0883073812449905"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2011.03.009"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.18","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e3283505b62"},{"key":"2025082704073414000_2015.jun16_1.bcr2014207796.19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0031913"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-207796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:07:43Z","timestamp":1756292863000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-207796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,16]]},"references-count":19,"alternative-id":["10.1136\/bcr-2014-207796"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-207796","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,6,16]]}}}