{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:26:59Z","timestamp":1765546019180,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,3,20]]},"abstract":"<jats:p>A 27-year-old woman, fourth gravida, with three prior consecutive vesicular moles was diagnosed with a recurrent vesicular mole on ultrasonography (USG) and had very low \u03b2-human chorionic gonadotropin (HCG) values. During suction evacuation no vesicles were seen and on repeat USG the patient was diagnosed to have fibroid uterus. She was discharged at request and advised to undergo MRI to rule out choriocarcinoma. The MRI was interpreted as fibroid uterus with degeneration. After 3\u2005weeks of suction evacuation, the patient presented with acute abdomen. She underwent emergency laparotomy for haemoperitoneum and was diagnosed as invasive mole with perforation; total hysterectomy was performed. Her \u03b2-HCG after laparotomy was more than 200\u2005000 mIU\/L, and the histopathological examination revealed choriocarcinoma. When methotrxate, adriamycin and cyclophosphamide (MAC) therapy was advised, the patient initially received methotrexate monotherapy; after three cycles her \u03b2-HCG started rising after an initial drop, and the patient required four cycles of EMACO to achieve remission.<\/jats:p>","DOI":"10.1136\/bcr-2014-208526","type":"journal-article","created":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T14:14:04Z","timestamp":1429193644000},"page":"bcr2014208526","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Missing choriocarcinoma may be easy but not suspecting it in a high-risk case can be potentially fatal"],"prefix":"10.1136","volume":"2015","author":[{"given":"Papa","family":"Dasari","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,4,16]]},"reference":[{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.06.073"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.2","doi-asserted-by":"crossref","first-page":"538","DOI":"10.4103\/0019-5359.19197","article-title":"Chroriocarcinoma with negative urinary and serum beta human chorionic gonadotropin (beta HCG)\u2014a case report","volume":"59","author":"Mehra","year":"2005","journal-title":"Indian J Med Sci"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.7863\/jum.2005.24.1.15","article-title":"Sonographic and Doppler imaging in the diagnosis and treatment of gestational trophoblastic disease: a 12 year experience","volume":"24","author":"Zhou","year":"2005","journal-title":"J Ultrasound Med"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0221-0363(05)81391-5"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.5","doi-asserted-by":"publisher","DOI":"10.4103\/0971-3026.54887"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2009.03.001"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.7","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3875"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.8","unstructured":"Berrocal L , Torino JR , Medrano S , et al . Invasive molar pregnancy and MRI: what every radiologist must know. Eur Soc Radiol. http:\/\/www.MyESR.org . doi:10.1594\/ecr2010\/C-1200"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.9","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-009-0968-5"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.10","doi-asserted-by":"publisher","DOI":"10.1159\/000330028"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.11","first-page":"58","article-title":"Postmortem diagnosis of gestation choriocarcinoma- a case report","volume":"29","author":"Shetty","year":"2007","journal-title":"JIAFM"},{"key":"2025082801181560000_2015.apr16_1.bcr2014208526.12","doi-asserted-by":"crossref","unstructured":"Behtash N , Ansari S , Sarvi F . Successful pregnancy after localised resection of perforated uterus in choriocarcinoma and a literature review. Int J Gynecol Cancer 2006;(16 Suppl 1):445\u20138. doi:10.1111\/j.1525-1438.2006.00367.x","DOI":"10.1111\/j.1525-1438.2006.00367.x"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-208526","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:18:25Z","timestamp":1756369105000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-208526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,16]]},"references-count":12,"alternative-id":["10.1136\/bcr-2014-208526"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-208526","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,4,16]]}}}