{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T15:14:11Z","timestamp":1772810051435,"version":"3.50.1"},"reference-count":19,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,3,16]]},"abstract":"<jats:p>Angiosarcoma is a highly aggressive and extremely rare neoplasm of the spleen, with a limited number of reported cases worldwide.<\/jats:p>\n               <jats:p>We report a case of a 69-year-old man who presented with progressive symptoms of fatigue, abdominal and back pain, anaemia and haemoperitoneum 1\u2005year following embolisation of the spleen for splenic rupture. Additional imaging and colonoscopy with biopsy revealed intra-abdominal fluid and a colonic adenocarcinoma. Diagnostic laparoscopy demonstrated a haemoperitoneum and colon carcinoma, after which splenectomy via laparotomy was performed. Pathology report revealed an angiosarcoma of the spleen with peritoneal tumour deposits.<\/jats:p>\n               <jats:p>Rupturing of a spleen may be due to an underlying disease. Therefore, the differential diagnosis of splenic rupture should include the possibility of a splenic tumour. The definitive diagnosis and treatment of a splenic angiosarcoma may require splenectomy, although prognosis is poor.<\/jats:p>","DOI":"10.1136\/bcr-2014-208956","type":"journal-article","created":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T11:30:58Z","timestamp":1428579058000},"page":"bcr2014208956","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Delayed diagnosis of angiosarcoma of the spleen: clinically presenting as recurrent haemoperitoneum following embolisation"],"prefix":"10.1136","volume":"2015","author":[{"given":"Verena","family":"Kornmann","sequence":"first","affiliation":[{"name":"Department of Surgery, Slingeland Hospital Doetinchem, Doetinchem, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"van Rijn","sequence":"additional","affiliation":[{"name":"Department of Radiology, Slingeland Hospital, Doetinchem, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dries","family":"Mulder","sequence":"additional","affiliation":[{"name":"Department of Pathology, Rijnstate Hospital, Arnhem, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koen","family":"Reijnders","sequence":"additional","affiliation":[{"name":"Department of Surgery, Slingeland Hospital Doetinchem, Doetinchem, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.1","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2010.0026"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199310000-00001"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.3","doi-asserted-by":"publisher","DOI":"10.1007\/BF02134657"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.4","first-page":"211","article-title":"Spontaneous splenic rupture secondary to angiosarcoma","volume":"83","author":"Buckner","year":"1990","journal-title":"J Okla State Med Assoc"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.5","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20419"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.6","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880178"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.7","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2351040308"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2007.05.003"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2013.10.035"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2013.09.003"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.11","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6737"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.12","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-11-53"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.13","first-page":"39","article-title":"Spontaneous rupture of spleen: histological, immunohistochemical and ultrastructural study","volume":"7","author":"Giordano","year":"2003","journal-title":"Adv Clin Path"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2011.12.016"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.15","doi-asserted-by":"publisher","DOI":"10.1148\/rg.244045006"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.16","doi-asserted-by":"publisher","DOI":"10.4132\/KoreanJPathol.2014.48.3.241"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.17","first-page":"477","article-title":"Triple synchronous malignant tumors. Hepatic leiomyosarcoma, splenic hemangiosarcoma and sigmoid colon cancer. Case report","volume":"154","author":"Kinoshita","year":"1988","journal-title":"Acta Chir Scand"},{"key":"2025082623212686000_2015.apr09_1.bcr2014208956.18","first-page":"218","article-title":"Primary splenic angiosarcoma\u2014the same diagnosis yielding two different clinical pictures. 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